Taylor dispersion analysis discloses the impairment of Aβ peptide aggregation by the presence of a fluorescent tag
Sign Up to like & getrecommendations! Published in 2022 at "ELECTROPHORESIS"
DOI: 10.1002/elps.202200192
Abstract: The use of fluorescently tagged amyloid peptides, implicated in Alzheimer's disease, to study their aggregation at low concentrations is a common method; however, the fluorescent tag should not introduce a bias in the aggregation process.… read more here.
Keywords: aggregation; dispersion analysis; aggregation process; peptide aggregation ... See more keywords
Dual-monitoring Glycosylation and Local pH in Live Cells by Metabolic Oligosaccharide Engineering with a Ratiometric Fluorescent Tag.
Sign Up to like & getrecommendations! Published in 2019 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.9b03047
Abstract: Glycosylation and local pH change play vital roles in many biological processes. Monitoring the distribution of glycosylated mole-cules and their local nanoenvironment pH in live cells would provide deep insights into cellular metabolism. In this… read more here.
Keywords: fluorescent tag; live cells; metabolic oligosaccharide; glycosylation ... See more keywords