Encapsulation of Fluorescently Labeled RNAs into Surface-Tethered Vesicles for Single-Molecule FRET Studies in TIRF Microscopy.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0278-2_1
Abstract: Imaging fluorescently labeled biomolecules on a single-molecule level is a well-established technique to follow intra- and intermolecular processes in time, usually hidden in the ensemble average. The classical approach comprises surface immobilization of the molecule… read more here.
Keywords: molecule; single molecule; microscopy; surface ... See more keywords
Synthesis of novel fluorescently labeled water-soluble fullerenes and their application to its cellar uptake and distribution properties
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Nanoparticle Research"
DOI: 10.1007/s11051-017-4098-x
Abstract: Fullerene is a well-known carbon nanomaterial, which can be potentially used for drug manufacture or delivery. Despite several successful examples of utilizing fullerene derivatives as drug candidate materials, their low water solubility under physiological conditions… read more here.
Keywords: synthesis novel; novel fluorescently; water; cellar uptake ... See more keywords
Development of a Fluorescently Labeled Aptamer Structure-Switching Assay for Sensitive and Rapid Detection of Gliotoxin.
Sign Up to like & getrecommendations! Published in 2019 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.8b05094
Abstract: Gliotoxin, one of the most toxic metabolites produced during the growth of Aspergillus fumigatus, can cause direct damage to the immune system and results in infection and spread of Aspergillus, or even leads to invasive… read more here.
Keywords: gliotoxin; detection; aptamer structure; detection gliotoxin ... See more keywords
Fluorescently Labeled Morphine Derivatives for Bioimaging Studies.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.7b01811
Abstract: Opioids, like morphine, are the mainstay analgesics for the treatment and control of pain. Despite this, they often exhibit severe side effects that limit dose; patients often become tolerant and dependent on these drugs, which… read more here.
Keywords: morphine derivatives; bioimaging studies; labeled morphine; receptor ... See more keywords
Imaging of Tie2 with a fluorescently labeled small molecule affinity ligand.
Sign Up to like & getrecommendations! Published in 2019 at "ACS chemical biology"
DOI: 10.1021/acschembio.9b00724
Abstract: The receptor tyrosine kinase inhibitor, Tie2, has significant roles in endothelial signaling and angiogenesis, and is relevant in the pathophysiology of several diseases. However, there are relatively few small molecule probes available to study Tie2,… read more here.
Keywords: small molecule; tie2 fluorescently; imaging tie2; tie2 ... See more keywords
Elucidating the Oligomerization and Cellular Interactions of a Trimer Derived from Aβ through Fluorescence and Mass Spectrometric Studies
Sign Up to like & getrecommendations! Published in 2022 at "ACS Chemical Neuroscience"
DOI: 10.1021/acschemneuro.2c00313
Abstract: Aβ oligomers play a central role in the neurodegeneration observed with Alzheimer’s disease. Our laboratory has developed covalently stabilized trimers derived from residues 17–36 of Aβ as model systems for studying Aβ oligomers. In the… read more here.
Keywords: elucidating oligomerization; microscopy; oligomerization cellular; fluorescently labeled ... See more keywords
Noncontact recognition of fluorescently labeled objects in deep tissue via a novel optical light beam arrangement
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0208236
Abstract: To date, few optical imaging systems are available in clinical practice to perform noninvasive measurements transcutaneously. Instead, functional imaging is performed using ionizing radiation or intense magnetic fields in most cases. The applicability of fluorescence… read more here.
Keywords: deep tissue; fluorescence; tissue; light ... See more keywords
A portable and high-sensitivity optical sensing system for detecting fluorescently labeled enterohaemorrhagic Escherichia coli Shiga toxin 2B-subunit
Sign Up to like & getrecommendations! Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0236043
Abstract: We developed a stand-alone, real-time optical detection device capable of reading fluorescence intensities from cell samples with high sensitivity and precision, for use as a portable fluorescent sensor for sensing fluorescently labeled enterohemorrhagic Escherichia coli… read more here.
Keywords: shiga; system; high sensitivity; escherichia coli ... See more keywords
The Invasion of Bacterial Biofilms into the Dentinal Tubules of Extracted Teeth Retrofilled with Fluorescently Labeled Retrograde Filling Materials
Sign Up to like & getrecommendations! Published in 2020 at "Applied Sciences"
DOI: 10.3390/app10196996
Abstract: In this study, we evaluated the invasion of bacteria into the dentinal tubules of retrofilled extracted human teeth, and the influence of different fluorescently labeled retrograde filling materials on the bacterial invasion and viability, by… read more here.
Keywords: penetration; retrograde filling; filling materials; labeled retrograde ... See more keywords
Small-Scale Preparation of Fluorescently Labeled Chemical Probes from Marine Cyclic Peptides, Kapakahines A and F
Sign Up to like & getrecommendations! Published in 2021 at "Marine Drugs"
DOI: 10.3390/md19020076
Abstract: A number of bioactive marine natural products have been isolated so far, but it is still difficult to disclose their modes of action. In this study, we prepared fluorescently labeled chemical probes from the cytotoxic… read more here.
Keywords: labeled chemical; marine cyclic; chemical probes; cyclic peptides ... See more keywords