Combining nano-differential scanning fluorimetry and microscale thermophoresis to investigate VDAC1 interaction with small molecules
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DOI: 10.1080/14756366.2022.2121821
Abstract: Abstract The mitochondrial voltage-dependent anion channel 1 (VDAC1) plays a central role in metabolism and apoptosis, which makes it a promising therapeutic target. Nevertheless, molecular mechanisms governing VDAC1 functioning remain unclear. Small-molecule ligands specifically interacting… read more here.
Keywords: vdac1; microscale thermophoresis; fluorimetry microscale; differential scanning ... See more keywords