Synthesis and evaluation of 3'-fluorinated 7-deazapurine nucleosides as antikinetoplastid agents.
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DOI: 10.1016/j.ejmech.2021.113290
Abstract: Kinetoplastid parasites are the causative agents of neglected tropical diseases with an unmet medical need. These parasites are unable to synthesize the purine ring de novo, and therefore rely on purine salvage to meet their… read more here.
Keywords: antikinetoplastid agents; deazapurine nucleosides; evaluation fluorinated; fluorinated deazapurine ... See more keywords