Novel fluorinated derivative of curcumin negatively regulates thioredoxin-interacting protein expression in retinal pigment epithelial and macrophage cells.
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DOI: 10.1016/j.bbrc.2020.08.114
Abstract: Thioredoxin-interacting protein (TXNIP) has multiple disease-associated functions including inducing oxidative stress by inhibiting the anti-oxidant and thiol reducing activity of thioredoxin (TRX), reducing cellular glucose transport, and is a component of the activated inflammasome complex.… read more here.
Keywords: thioredoxin interacting; thioredoxin; expression; interacting protein ... See more keywords