Synthesis of α-Fluorinated Imides via Direct Fluorohydroxylation of Ynamides.
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DOI: 10.1021/acs.orglett.9b01428
Abstract: A practical synthesis of α-fluorinated imides via the catalyst-free fluorohydroxylation of ynamides is developed. The reaction employs commercially available Selectfluor (F-TEDA-BF4) and H2O as the fluorine and hydroxyl sources, respectively. A broad range of aryl-… read more here.
Keywords: synthesis fluorinated; fluorohydroxylation ynamides; via direct; fluorinated imides ... See more keywords