Ring-Opening Fluorination of Isoxazoles.
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DOI: 10.1021/acs.orglett.2c01149
Abstract: A ring-opening fluorination of isoxazoles has been developed. Upon treatment of isoxazoles with an electrophilic fluorinating agent (Selectfluor), fluorination followed by deprotonation leads to tertiary fluorinated carbonyl compounds. This method features mild reaction conditions, good… read more here.
Keywords: opening fluorination; fluorination isoxazoles; ring opening; fluorination ... See more keywords