LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "fluorine atoms" as a keyword



Overcoming undesirable hERG affinity by incorporating fluorine atoms: A case of MAO-B inhibitors derived from 1 H-pyrrolo-[3,2-c]quinolines.

Sign Up to like & get
recommendations! Published in 2022 at "European journal of medicinal chemistry"

DOI: 10.1016/j.ejmech.2022.114329

Abstract: The incorporation of the fluorine motif is a strategy widely applied in drug design for modulating the activity, physicochemical parameters, and metabolic stability of chemical compounds. In this study, we attempted to reduce the affinity… read more here.

Keywords: mao inhibitors; mao; fluorine atoms; affinity ... See more keywords

Ultralong Room-Temperature Phosphorescence in Ca(II) Metal-Organic Frameworks Based on Nicotinic Acid Ligands.

Sign Up to like & get
recommendations! Published in 2024 at "Inorganic chemistry"

DOI: 10.1021/acs.inorgchem.4c03868

Abstract: In recent years, metal-organic framework (MOF) materials with long persistent luminescence (LPL) have inspired extensive attention and presented various applications in security systems, information anticounterfeiting, and biological imaging fields. However, obtaining LPL materials with ultralong… read more here.

Keywords: ultralong room; fluorine atoms; 5fca mof; room temperature ... See more keywords

Planar tetracoordinate fluorine atoms†

Sign Up to like & get
recommendations! Published in 2021 at "Chemical Science"

DOI: 10.1039/d1sc01325d

Abstract: Among the list of planar tetracoordinate atoms, fluorine is missing. So far, there are no theoretical or experimental reports suggesting their existence. Herein, we introduce the first six combinations (FIn4+, FTl4+, FGaIn3+, FIn2Tl2+, FIn3Tl+, and… read more here.

Keywords: fluorine atoms; planar tetracoordinate; tetracoordinate fluorine;

How does the combination of the nitro group and fluorine atoms affect the (co)crystallization behaviour of arylenediamines?

Sign Up to like & get
recommendations! Published in 2023 at "CrystEngComm"

DOI: 10.1039/d3ce00327b

Abstract: A series of phenylenediamines containing the NO2 group and 3 to 0 fluorine atoms and 18-crown-6 ether were used to study the dependence of the stoichiometry and supramolecular structure of... read more here.

Keywords: fluorine atoms; combination nitro; group fluorine; nitro group ... See more keywords

Fluorine Atoms on C6H5-Corrole Affect the Interaction with Mpro and PLpro Proteases of SARS-CoV-2: Molecular Docking and 2D-QSAR Approaches

Sign Up to like & get
recommendations! Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms231810936

Abstract: The chymotrypsin-like cysteine protease (3CLpro, also known as main protease—Mpro) and papain-like protease (PLpro) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been used as the main targets for screening potential synthetic inhibitors for… read more here.

Keywords: interaction mpro; aryl corrole; meso aryl; fluorine atoms ... See more keywords