Spirocyclic Iodonium Ylides for Fluorine-18 Radiolabeling of Non-Activated Arenes: From Concept to Clinical Research.
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DOI: 10.1002/tcr.202300072
Abstract: Positron emission tomography (PET) is a powerful imaging tool for drug discovery, clinical diagnosis, and monitoring of disease progression. Fluorine-18 is the most common radionuclide used for PET, but advances in radiotracer development have been… read more here.
Keywords: non activated; spirocyclic iodonium; fluorine radiolabeling; clinical research ... See more keywords
Synthesis, Fluorine-18 Radiolabeling, and In Vivo PET Imaging of a Hydrophilic Fluorosulfotetrazine
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DOI: 10.3390/ph16050636
Abstract: The development of 18F-fluorotetrazines, suitable for the radiolabeling of biologics such as proteins and antibodies by IEDDA ligation, represents a major challenge, especially for pre-targeting applications. The hydrophilicity of the tetrazine has clearly become a… read more here.
Keywords: synthesis fluorine; vivo; fluorine radiolabeling; 18f fluorosulfotetrazine ... See more keywords