Synthesis, α-glucosidase inhibition and in silico studies of some 4-(5-fluoro-2-substituted-1H-benzimidazol-6-yl)morpholine derivatives.
Sign Up to like & getrecommendations! Published in 2020 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2020.104002
Abstract: In this study, a new series of 4-(5-fluoro-2-substituted-1H-benzimidazol-6-yl)morpholine derivatives has been synthesized and screened for their α-glucosidase inhibitory potential. All molecules showed a considerable α-glucosidase inhibitory potential with IC50 values ranging from 20.46 ± 0.21 to 0.18 ± 0.01 µg/mL… read more here.
Keywords: silico studies; inhibition; fluoro substituted; morpholine derivatives ... See more keywords
Study of the structural and conformational properties of fluoro-substituted thioacetanilide derivatives
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DOI: 10.1016/j.molstruc.2020.128768
Abstract: Abstract The assessment of the influence of a halogen atom in the structural, vibrational and conformational properties of o-, m- and p-fluorothioacetanilide derivatives was achieved through different methodologies. For all compounds infrared (FTIR) and nuclear… read more here.
Keywords: substituted thioacetanilide; fluoro substituted; conformational properties; properties fluoro ... See more keywords
Electrical Properties of Fluoro-Substituted Perovskites Ba2 − 0.5xCaNbO5.5 −xFx
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DOI: 10.1134/s1023193518120108
Abstract: The effect of F--doping on the transport properties of perovskite-type complex oxides based on barium—calcium niobate Ba2CaNbO5.5 is analyzed. It is found that, regardless of the mechanism of introducing fluoride ions into the oxygen sublattice,… read more here.
Keywords: substituted perovskites; fluoro substituted; properties fluoro; ba2 5xcanbo5 ... See more keywords