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Published in 2021 at "Organic letters"
DOI: 10.1021/acs.orglett.1c01498
Abstract: Despite the development of artificial l-RNA/DNA as therapeutic molecules, the in-depth investigation on their chemical modifications is still limited. Here, we synthesize a chemically derivatized 2'-deoxy-2'-fluoro-l-uridine building block and incorporate it into oligonucleotides. Our thermo-denaturization…
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Keywords:
deoxy fluoro;
synthesis structural;
fluoro uridine;
fluoro ... See more keywords