Engaging α-Fluorocarboxylic Acids Directly in Decarboxylative C–C Bond Formation
Sign Up to like & getrecommendations! Published in 2020 at "ACS Catalysis"
DOI: 10.1021/acscatal.0c00789
Abstract: Fluorine-containing organic molecules, particularly those that bear (sp3)C–F bonds, are rapidly gaining prominence in modern chemical synthesis. Although extensive studies have been devoted to the ... read more here.
Keywords: directly decarboxylative; engaging fluorocarboxylic; bond formation; fluorocarboxylic acids ... See more keywords
Semirational Design of Fluoroacetate Dehalogenase RPA1163 for Kinetic Resolution of α-Fluorocarboxylic Acids on a Gram Scale
Sign Up to like & getrecommendations! Published in 2020 at "ACS Catalysis"
DOI: 10.1021/acscatal.9b04804
Abstract: Here the synthetic utility of fluoroacetate dehalogenase RPA1163 is explored for the production of enantiomerically pure (R)-α-fluorocarboxylic acids and (R)-α-hydroxylcarboxylic acids via kinetic ... read more here.
Keywords: fluorocarboxylic acids; dehalogenase rpa1163; fluoroacetate dehalogenase;
Silver-catalyzed monofluoroalkylation of heteroarenes with α-fluorocarboxylic acids: an insight into the solvent effect.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d1cc06466e
Abstract: A mild and efficient method for direct C-H monofluoroalkylation of heteroarenes with easily accessible and inexpensive α-fluorocarboxylic acids has been developed. This silver-catalyzed reaction affords mono- and bis-monofluoroalkylated heteroarenes in good yields under mild conditions,… read more here.
Keywords: monofluoroalkylation heteroarenes; monofluoroalkylation; silver catalyzed; solvent effect ... See more keywords