The in vitro anticancer activity and potential mechanism of action of 1-[(1R,2S)-2-fluorocyclopropyl]ciprofloxacin-(4-methyl/phenyl/benzyl-3-aryl)-1,2,4-triazole-5(4H)-thione hybrids.
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DOI: 10.2174/1568026620666200310123723
Abstract: AIMS To develop novel anticancer candidates which are sensitive to both drug-sensitive and drug-resistant cancers, a series of 1-[(1R, 2S)-2-fluorocyclopropyl]ciprofloxacin-(4-methyl/phenyl/benzyl-3-aryl)-1,2,4-triazole-5(4H)-thione hybrids were designed, synthesized and evaluated for their anticancer activity. BACKGROUND Chemotherapy is an essential… read more here.
Keywords: thione hybrids; fluorocyclopropyl ciprofloxacin; drug; triazole thione ... See more keywords