Fluorogenic Probe for Fast 3D Whole-Cell DNA-Paint
Sign Up to like & getrecommendations! Published in 2021 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2020.11.343
Abstract: DNA-PAINT is an increasingly popular super-resolution microscopy method that can acquire high-fidelity images at nanometer resolution. It suffers, however, from high background and very slow imaging speed, both of which can be attributed to the… read more here.
Keywords: probe fast; fluorogenic probe; dna; dna paint ... See more keywords
Kinetic and Conformational Insights into Islet Amyloid Polypeptide Self-Assembly Using a Biarsenical Fluorogenic Probe.
Sign Up to like & getrecommendations! Published in 2018 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.7b00827
Abstract: Amyloid fibril formation and tissue deposition are associated with many diseases. Studies have shown that prefibrillar intermediates, such as oligomers, are the most toxic proteospecies of the amyloidogenic cascade. Thus, understanding the mechanisms of formation… read more here.
Keywords: self assembly; cys; fluorogenic probe; kinetic conformational ... See more keywords
Ultrasensitive Fibroblast Activation Protein-α-Activated Fluorogenic Probe Enables Selective Imaging and Killing of Melanoma In Vivo.
Sign Up to like & getrecommendations! Published in 2022 at "ACS sensors"
DOI: 10.1021/acssensors.2c00126
Abstract: Melanoma is a malignant cancer with a high risk of metastasis and continued increase in death rates over the past decades, and its prognosis is highly related to the disease's stage, while early detection and… read more here.
Keywords: activation protein; melanoma; fap; fluorogenic probe ... See more keywords
A wash-free SNAP-tag fluorogenic probe based on the additive effects of quencher release and environmental sensitivity.
Sign Up to like & getrecommendations! Published in 2017 at "Chemical communications"
DOI: 10.1039/c7cc01483j
Abstract: A 1,8-naphthalimide-derived fluorogenic probe was reported to label SNAP-tag fusion proteins in living cells. The probe can rapidly label a SNAP-tag and exhibit a fluorescence increase of 36-fold due to the additive effects of environment… read more here.
Keywords: snap; additive effects; snap tag; fluorogenic probe ... See more keywords
Internal standard fluorogenic probe based on vibration-induced emission for visualizing PTP1B in living cells.
Sign Up to like & getrecommendations! Published in 2019 at "Chemical communications"
DOI: 10.1039/c9cc07680h
Abstract: Herein, as a proof of concept, we developed the first enzymatic VIE fluorogenic probe for protein tyrosine phosphatase 1B (PTP1B). The detection and imaging of PTP1B using VIE in living cells were both realized. Particularly… read more here.
Keywords: standard fluorogenic; probe; internal standard; fluorogenic probe ... See more keywords
A fluorogenic probe for tracking GSH flux in developing neurons.
Sign Up to like & getrecommendations! Published in 2019 at "Chemical communications"
DOI: 10.1039/c9cc07753g
Abstract: Understanding GSH flux in developing neurons is prerequisite to reveal its role in neuronal development but necessiates an ultrasensitive assay. By systematically exploring key structural factors determing probe sensitivity in live cells, we developed a… read more here.
Keywords: flux developing; gsh flux; probe; developing neurons ... See more keywords
A thiol-activated fluorogenic probe for detection of a target protein.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc02029g
Abstract: A novel fluorogenic probe for facile and efficient detection of a target protein that binds to a bioactive small molecule was developed. The probe was composed of a thiol-activated fluorogenic moiety bearing an alkyne tag… read more here.
Keywords: fluorogenic probe; detection target; protein; target protein ... See more keywords
Small-Molecule Fluorogenic Probe for the Detection of Hypochlorite and Its Application in the Bio-imaging of Human Breast Cancer Cells
Sign Up to like & getrecommendations! Published in 2023 at "Analytical Methods"
DOI: 10.1039/d3ay00646h
Abstract: A certain amount of hypochlorite can help to regulate the body’s defense system while excessive hypochlorite has some complex influence on health. Herein, a thiophene-derived biocompatible turn-on fluorescent probe (TPHZ)... read more here.
Keywords: small molecule; probe detection; detection hypochlorite; fluorogenic probe ... See more keywords