Novel Imidazole Phenoxyacetic Acids as Inhibitors of USP30 for Neuroprotection Implication via the Ubiquitin-Rho-110 Fluorometric Assay: Design, Synthesis, and In Silico and Biochemical Assays.
Sign Up to like & getrecommendations! Published in 2022 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.2c00076
Abstract: USP30, a deubiquitinating enzyme family, forfeits the ubiquitination of E3 ligase and Parkin on the surface of mitochondria. Inhibition of USP30 results in mitophagy and cellular clearance. Herein, by understanding structural requirements, we discovered potential… read more here.
Keywords: synthesis; novel imidazole; fluorometric assay; 110 fluorometric ... See more keywords
Quantitative Evaluation of Ultrasound-Assisted Extraction of 1,3-β-glucans from Dictyophora indusiata Using an Improved Fluorometric Assay
Sign Up to like & getrecommendations! Published in 2019 at "Polymers"
DOI: 10.3390/polym11050864
Abstract: In the present study, an improved fluorometric assay based on aniline blue dye for the specific, accurate, and rapid quantification of 1,3-β-glucans in edible mushrooms was developed and fully validated. Furthermore, the improved method was… read more here.
Keywords: extraction; improved fluorometric; dictyophora indusiata; fluorometric assay ... See more keywords