Interaction between a fluoroquinolone derivative KG022 and RNAs: Effect of base pairs 3′ adjacent to the bulged residues
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DOI: 10.3389/fmolb.2023.1145528
Abstract: RNA-targeted small molecules are a promising modality in drug discovery. Recently, we found that a fluoroquinolone derivative, KG022, can bind to RNAs with bulged C or G. To clarify the RNA specificity of KG022, we… read more here.
Keywords: fluoroquinolone derivative; base pairs; rna; effect base ... See more keywords