Topical Combination of Fluorouracil and Calcipotriene as a Palliative Therapy for Refractory Extramammary Paget Disease
Sign Up to like & getrecommendations! Published in 2019 at "JAMA Dermatology"
DOI: 10.1001/jamadermatol.2018.4793
Abstract: Importance Extramammary Paget disease (EMPD), a rare intraepithelial adenocarcinoma, poses a therapeutic challenge with high postoperative recurrence rates and a limited number of effective local treatment options. Objective To describe the use and efficacy of… read more here.
Keywords: combination; disease; fluorouracil; extramammary paget ... See more keywords
Enhancing the Management of Metastatic Tumors by Robust Co-delivery of 5-fluorouracil/microRNA-10b inhibitor Using EGFR-targeted Nanovehicles.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202202989
Abstract: Invasion and metastasis of colorectal cancer (CRC) are the leading causes of death of patients with CRC. 5-fluorouracil (5-FU) has been widely used in clinic practice as the basic chemotherapy drug for CRC. However, it… read more here.
Keywords: metastasis; egfr targeted; 10b inhibitor; microrna 10b ... See more keywords
Cardioprotective effect of silymarin nanoemulsion on 5-fluorouracil-induced cardiotoxicity in rats.
Sign Up to like & getrecommendations! Published in 2022 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202200060
Abstract: 5-Fluorouracil (5-FU)-associated cardiotoxicity has been ranked as the second most common cause of cardiotoxicity induced by chemotherapeutic drugs after anthracyclines. In the present study, we investigated the protective impacts of silymarin (SIL) and silymarin nanoemulsion… read more here.
Keywords: fluorouracil; silymarin nanoemulsion; sil sln; cardiotoxicity ... See more keywords
Synthesis and antimicrobial testing of 5-fluorouracil derivatives.
Sign Up to like & getrecommendations! Published in 2023 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202300103
Abstract: Antibiotic resistance has increased the demand for novel treatments against multidrug-resistant microorganisms. In the research literature, 5-fluorouracil (5-FU) was proposed as an alternative due to its intrinsic antibacterial property. However, given its toxicity profile at… read more here.
Keywords: fluorouracil derivatives; testing fluorouracil; antimicrobial testing; synthesis antimicrobial ... See more keywords
Graphene oxide‐l‐arginine nanogel: A pH‐sensitive fluorouracil nanocarrier
Sign Up to like & getrecommendations! Published in 2019 at "Biotechnology and Applied Biochemistry"
DOI: 10.1002/bab.1768
Abstract: Nowadays, putting forward an accurate cancer therapy method with minimal side effects is an important topic of research. Nanostructures, for their ability in controlled and targeted drug release on specific cells, are critical materials in… read more here.
Keywords: graphene oxide; arginine nanogel; nanogel sensitive; oxide arginine ... See more keywords
Determination of 5-fluorocytosine, 5-fluorouracil and 5-fluorouridine in hospital wastewater by LC-MS.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of separation science"
DOI: 10.1002/jssc.202000144
Abstract: Chemotherapeutics are pharmaceutical compounds whose occurrence in the environment is of growing concern because of the increase in treatments against cancer diseases. They can reach the aquatic ecosystems after passing through wastewater treatment plants without… read more here.
Keywords: fluorocytosine; fluorouridine hospital; wastewater; fluorouracil ... See more keywords
Efficacy and safety of neoadjuvant chemotherapy with oxaliplatin, 5-fluorouracil, and levofolinate for T3 or T4 stage II/III rectal cancer: the FACT trial
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Chemotherapy and Pharmacology"
DOI: 10.1007/s00280-017-3243-7
Abstract: PurposeA multicenter phase II clinical study was performed in patients with T3 or T4 stage II/III rectal cancer to evaluate the efficacy and safety of neoadjuvant chemotherapy with 5-fluorouracil, levofolinate, and oxaliplatin (mFOLFOX6).MethodsPatients received four… read more here.
Keywords: chemotherapy; rectal cancer; fluorouracil; rate ... See more keywords
5-Fluorouracil disrupts ovarian preantral follicles in young C57BL6J mice
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Chemotherapy and Pharmacology"
DOI: 10.1007/s00280-020-04217-7
Abstract: 5-Fluorouracil (5-FU), an anti-cancer drug, has been used for hepatoblastoma (HB) chemotherapy in children, who may have impaired ovarian follicle pool reserve with lasting effects to reproduction. Therefore, this study aimed to investigate 5-FU effects… read more here.
Keywords: preantral follicles; bax bcl2; fluorouracil; ovarian preantral ... See more keywords
Efficacy of postoperative management with 5-fluorouracil injections after XEN Gel Stent implantation
Sign Up to like & getrecommendations! Published in 2019 at "International Ophthalmology"
DOI: 10.1007/s10792-019-01168-8
Abstract: Purpose To evaluate the efficacy of postoperative management with 5-fluorouracil injections after XEN Gel Stent implantation. Methods Prospective real-world evidence study included 39 eyes (of 36 patients) with primary open-angle glaucoma without previous glaucoma surgery… read more here.
Keywords: postoperative management; mmhg; fluorouracil; fluorouracil injections ... See more keywords
Capecitabine Versus Continuous Infusion Fluorouracil for the Treatment of Advanced or Metastatic Colorectal Cancer: a Meta-analysis
Sign Up to like & getrecommendations! Published in 2018 at "Current Treatment Options in Oncology"
DOI: 10.1007/s11864-018-0597-y
Abstract: Opinion statementNowadays, systemic chemotherapy with intravenous (IV) 5-fluorouracil (5-FU) remains the most commonly prescribed treatment for metastatic colorectal cancers (CRC), in combination with other cytotoxic drugs. 5-FU can be administered through a bolus injection or… read more here.
Keywords: metastatic colorectal; continuous infusion; treatment; capecitabine ... See more keywords
Fluorouracil Filtering Surgery Study One-Year Follow-up.
Sign Up to like & getrecommendations! Published in 2018 at "American journal of ophthalmology"
DOI: 10.1016/j.ajo.2017.12.021
Abstract: Two hundred thirteen patients participated in the Fluorouracil Filtering Surgery Study, a randomized clinical trial, to determine the efficacy and safety of subconjunctivally injected 5-fluorouracil after filtering surgery in eyes with poor prognoses. Twenty-eight (27%)… read more here.
Keywords: fluorouracil filtering; surgery study; one year; fluorouracil ... See more keywords