Articles with "fluorouracil resistance" as a keyword



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Tumor‐derived extracellular vesicles confer 5‐fluorouracil resistance in esophageal cancer via long noncoding RNA AC116025.2 delivery

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Published in 2022 at "Molecular Carcinogenesis"

DOI: 10.1002/mc.23469

Abstract: 5‐Fluorouracil (5‐FU) resistance is one of the main causes for treatment failure in esophageal cancer (EC). Here, we intended to elucidate the mechanism of tumor‐derived extracellular vesicles (TEVs)‐encapsulated long noncoding RNAs (lncRNAs) AC116025.2 in 5‐FU… read more here.

Keywords: esophageal cancer; fluorouracil resistance; resistance; ac116025 ... See more keywords
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Insulin reverses choriocarcinoma 5- fluorouracil resistance.

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Published in 2021 at "Bioengineered"

DOI: 10.1080/21655979.2021.1931643

Abstract: Choriocarcinoma (CC) is a gestational trophoblastic tumor secondary to a gravid or non-gravid pregnancy. It is characterized by rapid growth, high invasion, and high metastatic potential and chemotherapy resistance that significantly affect survival rate of… read more here.

Keywords: insulin; fluorouracil resistance; resistance; reverses choriocarcinoma ... See more keywords
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Circ_0003998 upregulates ARK5 expression to elevate 5-Fluorouracil resistance in hepatocellular carcinoma through binding to miR-513a-5p

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Published in 2022 at "Anti-Cancer Drugs"

DOI: 10.1097/cad.0000000000001359

Abstract: Chemoresistance has limited clinical treatment of cancer patients. This study aimed to research the regulatory function of circ_0003998 in 5-Fluorouracil (5-FU) resistance. Circ_0003998, microRNA-513a-5p (miR-513a-5p) and AMPK-Related Protein Kinase 5 (ARK5) levels were assayed via… read more here.

Keywords: hepatocellular carcinoma; circ 0003998; mir 513a; fluorouracil resistance ... See more keywords
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MicroRNA-155-5p Contributes to 5-Fluorouracil Resistance Through Down-Regulating TP53INP1 in Oral Squamous Cell Carcinoma

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Published in 2021 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2021.706095

Abstract: The anticancer drug 5-fluorouracil (5-FU) resistance is a major obstacle to reducing the effectiveness of cancer treatment, and its detailed mechanism has not been fully elucidated. Here, in 5-FU-resistant human oral squamous cell carcinoma (OSCC)… read more here.

Keywords: fluorouracil resistance; expression; hsc3 cells; mir 155 ... See more keywords
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ZBTB7 evokes 5-fluorouracil resistance in colorectal cancer through the NF‑κB signaling pathway.

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Published in 2018 at "International journal of oncology"

DOI: 10.3892/ijo.2018.4521

Abstract: Zinc finger and BTB domain containing 7A (ZBTB7), a POZ/BTB and Krüppel erythroid myeloid oncogenic factor, is critical for the tumorigenicity and progression of various cancer types. ZBTB7 has been reported to promote the cell… read more here.

Keywords: zbtb7; fluorouracil resistance; resistance crc; resistance ... See more keywords
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RNA-Seq profiling of circular RNAs in human colorectal cancer 5-fluorouracil resistance and potential biomarkers

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Published in 2022 at "World Journal of Gastrointestinal Oncology"

DOI: 10.4251/wjgo.v14.i3.678

Abstract: BACKGROUND Colorectal cancer (CRC) is a commonly diagnosed cancer of the digestive system worldwide. Although chemotherapeutic agents and targeted therapeutic drugs are currently available for CRC treatment, drug resistance is a problem that cannot be… read more here.

Keywords: circrna; fluorouracil resistance; colorectal cancer; resistance ... See more keywords