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Published in 2020 at "Therapeutic Drug Monitoring"
DOI: 10.1097/ftd.0000000000000788
Abstract: 5-Fluorouracil (5-FU) response prediction and therapeutic drug monitoring (TDM) are required to minimize toxicity while preserving efficacy. Conventional 5-FU dose normalization uses body surface area (BSA). It is characterized by up to 100-fold inter-individual variability…
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Keywords:
response;
toxicity;
prediction;
response toxicity ... See more keywords