Neurotoxicity and mode of action of fluralaner on honeybee Apis mellifera L.
Sign Up to like & getrecommendations! Published in 2019 at "Pest management science"
DOI: 10.1002/ps.5483
Abstract: BACKGROUND Fluralaner, a novel pesticide that targets the γ-aminobutyric acid (GABA) receptor (GABAR) subunit of resistant to dieldrin (RDL), exhibits strong potential to be an insecticide to control agricultural insect pests. However, the risk and… read more here.
Keywords: honeybee apis; apis mellifera; action fluralaner; fluralaner honeybee ... See more keywords
Theoretical and Experimental Study of Molecular Interactions of Fluralaner with Lipid Membranes.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c06811
Abstract: Fluralaner is a relatively new insecticide belonging to the isoxazoline group, whose action mechanism involves the blocking of GABAA-receptors in the insect nervous system. Because of its high hydrophobicity, fluralaner could bioaccumulate and reach toxic… read more here.
Keywords: fluralaner lipid; fluralaner; study molecular; theoretical experimental ... See more keywords
N318L Blocks the Interaction of Fluralaner but Not Broflanilide or Fipronil with the Insect GABA Receptor In Vivo.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.4c06478
Abstract: Fluralaner is a novel insecticide targeting the ionotropic GABA receptor (GABAR) subunit, RDL. A recent study revealed that N316L, a substitution of asparagine (N) with leucine (L), in the second transmembrane (M2)-spanning region reduced the… read more here.
Keywords: vivo; fluralaner; gaba receptor; broflanilide fipronil ... See more keywords
The effect of fluralaner treatment of small mammals on the endemic cycle of Borrelia burgdorferi in a natural environment
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Medical Entomology"
DOI: 10.1093/jme/tjae091
Abstract: Among approaches aimed at reducing Lyme disease risk in the environment, those targeting reservoirs of Borrelia burgdorferi Johnson are promising because they have the potential to reduce both the density of questing Ixodes scapularis Say… read more here.
Keywords: environment; effect; borrelia burgdorferi; fluralaner ... See more keywords
Efficacy of oral fluralaner (Bravecto) against Tunga penetrans in dogs: A negative control, randomized field study in an endemic community in Brazil
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0010251
Abstract: The sand flea Tunga penetrans is one of the zoonotic agents of tungiasis, a parasitic skin disease of humans and animals. The dog is one of its main reservoirs. This negatively controlled, randomized, double-masked clinical… read more here.
Keywords: fluralaner; tunga penetrans; day; community brazil ... See more keywords
Effectiveness of fluralaner treatment regimens for the control of canine Chagas disease: A mathematical modeling study
Sign Up to like & getrecommendations! Published in 2023 at "PLOS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0011084
Abstract: Background Canine Chagas disease is caused by the protozoan parasite Trypanosoma cruzi and transmitted by insect triatomine vectors known as kissing bugs. The agent can cause cardiac damage and long-term heart disease and death in… read more here.
Keywords: fluralaner; disease; treatment regimens; transmission ... See more keywords
Pharmacokinetics and preliminary safety of single-dose oral fluralaner at 10 and 25 mg/kg in healthy horses revealed no adverse reactions.
Sign Up to like & getrecommendations! Published in 2025 at "American journal of veterinary research"
DOI: 10.2460/ajvr.25.06.0200
Abstract: Objective To determine the safety and pharmacokinetics of a single dose of the oral ectoparasiticide fluralaner at 10 and 25 mg/kg in healthy horses. Methods 12 clinically healthy university-owned horses, 9 to 17 years of… read more here.
Keywords: single dose; dose oral; fluralaner; healthy horses ... See more keywords
Fecal elimination of fluralaner in different carnivore species after oral administration
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Veterinary Science"
DOI: 10.3389/fvets.2024.1279844
Abstract: Fluralaner is a recent external parasiticide, first of a new class of drugs (isoxazoline parasiticides). It is widely used in companion animals both for its wide spectrum (fleas, ticks and other mites) but also for… read more here.
Keywords: fecal elimination; fluralaner different; fluralaner; elimination fluralaner ... See more keywords