The influence of genetic polymorphisms in drug metabolism enzymes and transporters on the pharmacokinetics of different fluvastatin formulations
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DOI: 10.1016/j.ajps.2019.06.002
Abstract: The purpose of the present study was to investigate the impact of genetic polymorphism on fluvastatin pharmacokinetics. In addition, we compared the fluvastatin pharmacokinetics differences between extended-release (ER) 80 mg tablet and immediate-release (IR) 40 mg capsule… read more here.
Keywords: genetic polymorphisms; drug metabolism; fluvastatin; slco1b1 ... See more keywords
Fluvastatin-Pretreated Donor Cells Attenuated Murine aGVHD by Balancing Effector T Cell Distribution and Function under the Regulation of KLF2
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DOI: 10.1155/2020/7619849
Abstract: Prevention of acute graft-versus-host disease (aGVHD) after allogeneic hematopoietic stem cell transplantation (allo-HSCT) is still to be explored. Statins are potent immunomodulatory agents that hold promise as novel and safe agents for aGVHD prophylaxis, yet… read more here.
Keywords: cell; fluvastatin pretreated; donor cells; fluvastatin ... See more keywords