Inference of dynamic macroscopic models of cell metabolism based on elementary flux modes analysis
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical Engineering Journal"
DOI: 10.1016/j.bej.2019.107325
Abstract: Abstract This study aims at providing a methodology based on both data- and knowledge-driven approaches to build dynamic macroscopic models of cell cultures. This methodology proceeds in three steps. A principal component analysis is first… read more here.
Keywords: elementary flux; methodology; models cell; flux modes ... See more keywords
Isotopic labelling reveals the efficient adaptation of wheat root TCA cycle flux modes to match carbon demand under ammonium nutrition
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-45393-8
Abstract: Proper carbon (C) supply is essential for nitrogen (N) assimilation especially when plants are grown under ammonium (NH4+) nutrition. However, how C and N metabolic fluxes adapt to achieve so remains uncertain. In this work,… read more here.
Keywords: flux modes; ammonium nutrition; nutrition; ammonium ... See more keywords
Boosting the extraction of elementary flux modes in genome-scale metabolic networks using the linear programming approach
Sign Up to like & getrecommendations! Published in 2020 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btaa280
Abstract: Abstract Motivation Elementary flux modes (EFMs) are a key tool for analyzing genome-scale metabolic networks, and several methods have been proposed to compute them. Among them, those based on solving linear programming (LP) problems are… read more here.
Keywords: flux modes; genome scale; elementary flux; linear programming ... See more keywords