Fluoxetine exposure disrupts food intake and energy storage in the cichlid fish Cichlasoma dimerus (Teleostei, Cichliformes).
Sign Up to like & getrecommendations! Published in 2019 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2019.124609
Abstract: Human pharmaceuticals are pollutants of special concern due to their widespread consumption over the last decades, their high persistence in the environment, and the reported alterations produced on non-target organism. The antidepressant fluoxetine (FLX) exerts… read more here.
Keywords: energy storage; dimerus; flx; food ... See more keywords
Left atrial appendage closure in patients with prohibitive anatomy: Insights from PINNACLE FLX.
Sign Up to like & getrecommendations! Published in 2021 at "Heart rhythm"
DOI: 10.1016/j.hrthm.2021.02.022
Abstract: BACKGROUND Watchman 2.5 (Boston Scientific Inc, Marlborough, MA) implant success approaches 95% in registries, yet many patients are not attempted because of complex left atrial appendage (LAA) anatomy. Watchman FLX can expand the range of… read more here.
Keywords: closure; flx; anatomy; failed watchman ... See more keywords
Employ FTIR spectroscopic method for determination of certain multiple sclerosis medications in plasma and pharmaceutical formulations
Sign Up to like & getrecommendations! Published in 2021 at "Microchemical Journal"
DOI: 10.1016/j.microc.2021.106329
Abstract: Abstract A selective, simple, rapid, green, cost-effective, and non-destructive assay was proposed for the simultaneous quantitation of Fampridine (FPN), Dexamethasone (DMS), and Fluoxetine (FLX) in spiked human plasma and commercial dosage forms without interference from… read more here.
Keywords: flx; method; plasma pharmaceutical; pharmaceutical formulations ... See more keywords
Fluoxetine administration during adolescence attenuates cognitive and synaptic deficits in adult 3×TgAD mice
Sign Up to like & getrecommendations! Published in 2017 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2017.08.037
Abstract: &NA; Fluoxetine (FLX) has broad neurobiological functions and neuroprotective effects; however, the preventive effects of FLX on cognitive impairments in Alzheimer's disease (AD) have not been reported. Here, we studied whether adolescent administration of fluoxetine… read more here.
Keywords: tgad mice; administration; flx; adolescence ... See more keywords
Perinatal fluoxetine exposure changes social and stress-coping behavior in adult rats housed in a seminatural environment
Sign Up to like & getrecommendations! Published in 2019 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2019.03.037
Abstract: ABSTRACT The use of selective serotonin reuptake inhibitors (SSRI) during pregnancy has increased tremendously, but the consequences for the offspring remain largely unclear. Several studies have described potential effects of perinatal SSRI‐exposure on neurobehavioral outcomes… read more here.
Keywords: stress coping; flx; exposure; seminatural environment ... See more keywords
Anxiogenic-like effects of fluoxetine render adult male rats vulnerable to the effects of a novel stress
Sign Up to like & getrecommendations! Published in 2017 at "Pharmacology Biochemistry and Behavior"
DOI: 10.1016/j.pbb.2016.12.007
Abstract: ABSTRACT Fluoxetine (FLX) has paradoxical anxiogenic‐like effects during the acute phase of treatment. In adolescent (35 d‐old) male rats, the stress‐like effects induced by short‐term (3 d–4 d) FLX treatment appear to involve up‐regulation of… read more here.
Keywords: adult; male rats; flx; like effects ... See more keywords
Postpartum corticosterone and fluoxetine shift the tryptophan-kynurenine pathway in dams
Sign Up to like & getrecommendations! Published in 2021 at "Psychoneuroendocrinology"
DOI: 10.1016/j.psyneuen.2021.105273
Abstract: Perinatal depression (PND) affects 15% of mothers. Selective serotonin reuptake inhibitors (SSRIs) are currently the first-line of treatment for PND but are not always efficacious. Previously, we found significant reductions in plasma tryptophan concentrations and… read more here.
Keywords: tryptophan kynurenine; flx; treatment; efficacy ... See more keywords
Cortisol disruption and transgenerational alterations in the expression of stress-related genes in zebrafish larvae following fluoxetine exposure.
Sign Up to like & getrecommendations! Published in 2019 at "Toxicology and applied pharmacology"
DOI: 10.1016/j.taap.2019.114742
Abstract: Fluoxetine (FLX), the active ingredient in well-known therapeutic drugs such as Prozac, is highly prescribed worldwide to treat affective disorders even among pregnant women and adolescents. Given that FLX readily crosses the placenta, a fetus… read more here.
Keywords: cortisol; flx; exposure; larvae ... See more keywords
Adolescent fluoxetine treatment mediates a persistent anxiety-like outcome in female C57BL/6 mice that is ameliorated by fluoxetine re-exposure in adulthood
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-87378-6
Abstract: The objective of this study was to evaluate whether juvenile fluoxetine (FLX) exposure induces long-term changes in baseline responses to anxiety-inducing environments, and if so, whether its re-exposure in adulthood would ameliorate this anxiety-like phenotype.… read more here.
Keywords: flx; anxiety; exposure adulthood; exposure ... See more keywords
In vitro and in vivo evaluation of taste-masked orodispersible tablets of fluoxetine hydrochloride for the treatment of depression
Sign Up to like & getrecommendations! Published in 2021 at "Drug Development and Industrial Pharmacy"
DOI: 10.1080/03639045.2021.1908336
Abstract: Abstract Aim Fluoxetine (FLX) has become the first-line drug in the pharmacotherapy of patients with depression. However, it has a strong unpleasant bitter taste, leading to the failure to complete the therapy. In this study,… read more here.
Keywords: taste; flx; orodispersible tablets; study ... See more keywords
How Does Chemoradiotherapy Following Induction FOLFIRINOX Improve the Results in Resected Borderline or Locally Advanced Pancreatic Adenocarcinoma? An AGEO-FRENCH Multicentric Cohort
Sign Up to like & getrecommendations! Published in 2018 at "Annals of Surgical Oncology"
DOI: 10.1245/s10434-018-6931-6
Abstract: BackgroundPatients with borderline (BR) or locally advanced (LA) pancreatic adenocarcinoma (PAC) are often treated with induction FOLFIRINOX (FLX). However, the role of additional preoperative chemoradiotherapy (CRT) is controversial. The aim of this study is to… read more here.
Keywords: flx; borderline locally; additional crt; crt ... See more keywords