Type I interferon signaling attenuates regulatory T cell function in viral infection and in the tumor microenvironment
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DOI: 10.1371/journal.ppat.1006985
Abstract: Regulatory T cells (Tregs) play a cardinal role in the immune system by suppressing detrimental autoimmune responses, but their role in acute, chronic infectious diseases and tumor microenvironment remains unclear. We recently demonstrated that IFN-α/β… read more here.
Keywords: flxfoxp3yfp cre; infection; cre mice; ifnarfl flxfoxp3yfp ... See more keywords