Delving into Macrolide Binding Affinities and Associated Structural Modulations in Erythromycin Esterase C: Insights into the Venus Flytrap Mechanism
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DOI: 10.1021/acs.jcim.4c01523
Abstract: Since their inception in antibacterial therapy, macrolide-based antibiotics have significantly shaped the evolutionary pathways of pathogenic bacteria, driving them to develop diverse antimicrobial resistance (AMR) mechanisms. Among these, macrolide esterase, commonly referred to as erythromycin… read more here.
Keywords: macrolide binding; flytrap mechanism; venus flytrap; erythromycin esterase ... See more keywords