Identification of three linear B cell epitopes against non-structural protein 3ABC of FMDV using monoclonal antibodies
Sign Up to like & getrecommendations! Published in 2019 at "Applied Microbiology and Biotechnology"
DOI: 10.1007/s00253-019-10081-0
Abstract: Foot-and-mouth disease virus (FMDV) has led to serious losses in the farming industry worldwide, particularly in cattle and swine. In developing countries, the control and eradication of FMD rely upon vaccination, in which the inactivated… read more here.
Keywords: cell epitopes; linear cell; monoclonal antibodies; three linear ... See more keywords
Recombinant T7 Phage with FMDV AKT-III Strain VP1 Protein is a Potential FMDV Vaccine
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology Letters"
DOI: 10.1007/s10529-020-03012-x
Abstract: Objectives The capsid protein (VP1) of the foot-and-mouth (FMD) AKT-III strain was expressed on the surface of the T7 phage capsid (AKT-T7 strain) and the potential of AKT-T7 strain as an FMD vaccine was evaluated.… read more here.
Keywords: akt; phage; strain; vaccine ... See more keywords
Development of a competitive ELISA method based on VLPs detecting the antibodies of serotype A FMDV.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of virological methods"
DOI: 10.1016/j.jviromet.2021.114406
Abstract: Foot-and-mouth disease (FMD) is the highly contagious disease of cloven-hoofed animal that brings considerable economic losses to the animal husbandry. So FMD surveillance which relying on accurate diagnosis is important. Most producing the diagnostic antigen… read more here.
Keywords: based vlps; competitive elisa; serotype fmdv; antibodies serotype ... See more keywords
Duration of protection and humoral immunity induced by an adenovirus-vectored subunit vaccine for foot-and-mouth disease (FMD) in Holstein steers.
Sign Up to like & getrecommendations! Published in 2019 at "Vaccine"
DOI: 10.1016/j.vaccine.2019.08.017
Abstract: Foot-and-mouth disease (FMD) is a highly contagious viral infection of cloven hooved animals that continues to cause economic disruption in both endemic countries or when introduced into a formally FMD free country. Vaccines that protect… read more here.
Keywords: immunity; vaccine; disease; vaccination ... See more keywords
Inter-laboratory validation of foot-and-mouth disease diagnostic capability in Germany.
Sign Up to like & getrecommendations! Published in 2017 at "Veterinary microbiology"
DOI: 10.1016/j.vetmic.2017.03.001
Abstract: Germany has been free from foot-and-mouth disease virus (FMDV) without vaccination since 1992, but diagnostic capability at regional laboratories is maintained for FMDV exclusion in suspect cases and as surge capacity for outbreak preparedness. A… read more here.
Keywords: diagnostic capability; foot mouth; fmdv; mouth disease ... See more keywords
Enhanced protection against FMDV in cattle after prime- boost vaccination based on mucosal and inactivated FMD vaccine.
Sign Up to like & getrecommendations! Published in 2017 at "Veterinary microbiology"
DOI: 10.1016/j.vetmic.2017.08.014
Abstract: Improved immunization and control strategies and platforms are greatly needed for foot and mouth disease virus (FMDV) and mucosal vaccines propose an effective strategy for the control FMDV by blocking viral entry. In this study,… read more here.
Keywords: protection; mucosal; inactivated fmd; mucosal vaccine ... See more keywords
A review of foot-and-mouth disease virus (FMDV) testing in livestock with an emphasis on the use of alternative diagnostic specimens
Sign Up to like & getrecommendations! Published in 2018 at "Animal Health Research Reviews"
DOI: 10.1017/s1466252318000063
Abstract: Abstract Foot-and-mouth disease virus (FMDV) remains an important pathogen of livestock more than 120 years after it was identified, with annual costs from production losses and vaccination estimated at €5.3–€17 billion (US$6.5–US$21 billion) in FMDV-endemic… read more here.
Keywords: disease virus; livestock; foot mouth; mouth disease ... See more keywords
The antibody response induced FMDV vaccines in sheep correlates with early transcriptomic responses in blood.
Sign Up to like & getrecommendations! Published in 2020 at "NPJ vaccines"
DOI: 10.1038/s41541-019-0151-3
Abstract: Foot and mouth disease (FMD) is a highly contagious viral disease with high economic impact, representing a major threat for cloven-hooved mammals worldwide. Vaccines based on adjuvanted inactivated virus (iFMDV) induce effective protective immunity implicating… read more here.
Keywords: response induced; antibody; ad5 fmdv; vaccine ... See more keywords
Review of the Global Distribution of Foot‐and‐Mouth Disease Virus from 2007 to 2014
Sign Up to like & getrecommendations! Published in 2017 at "Transboundary and Emerging Diseases"
DOI: 10.1111/tbed.12373
Abstract: Foot-and-mouth disease (FMD) virus affects livestock worldwide. There are seven different serotypes, each with a diversity of topotypes, genetic lineages and strains. Some lineages have different properties that may contribute to sporadic spread beyond their… read more here.
Keywords: foot mouth; fmd; disease; mouth disease ... See more keywords
Polymerase Fidelity Contributes to Foot-and-Mouth Disease Virus Pathogenicity and Transmissibility In Vivo
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Virology"
DOI: 10.1128/jvi.01569-20
Abstract: Among the seven serotypes of FMDV, serotype O FMDV have the broadest distribution worldwide, which could be due to their high virulence and transmissibility induced by high genetic diversity. In this paper, we generated a… read more here.
Keywords: genetic diversity; fmdv; polymerase; transmissibility ... See more keywords
Heat Shock Protein 60 Is Involved in Viral Replication Complex Formation and Facilitates Foot and Mouth Virus Replication by Stabilizing Viral Nonstructural Proteins 3A and 2C
Sign Up to like & getrecommendations! Published in 2022 at "mBio"
DOI: 10.1128/mbio.01434-22
Abstract: FMDV is the leading cause of the foot-and-mouth disease (FMD), affecting cloven-hoofed animals with high morbidity and mortality. We determined that HSP60 is required for efficient viral RNA replication and mRNA translation during FMDV infection.… read more here.
Keywords: foot mouth; viral replication; replication; fmdv ... See more keywords