Ocular inflammatory diseases in children with familial Mediterranean fever: a true association or a coincidence?
Sign Up to like & getrecommendations! Published in 2021 at "International Ophthalmology"
DOI: 10.1007/s10792-021-02111-6
Abstract: To describe the characteristics of patients with familial Mediterranean fever (FMF) with concurrent ocular inflammatory disease (OID) and to analyze possible relations between them. Clinical data were extracted from electronic medical records. Additionally, the medical… read more here.
Keywords: ocular inflammatory; familial mediterranean; inflammatory diseases; mediterranean fever ... See more keywords
Longitudinal analysis of serum interleukin‐18 in patients with familial Mediterranean fever carrying MEFV mutations in exon 10
Sign Up to like & getrecommendations! Published in 2018 at "Cytokine"
DOI: 10.1016/j.cyto.2017.10.007
Abstract: Background: Familial Mediterranean fever (FMF) is an autoinflammatory disease caused by mutations in the MEFV gene. Mutations in exon 10 are associated with typical FMF phenotypes, and patients with exon 10 mutations have higher serum… read more here.
Keywords: mutations exon; familial mediterranean; exon mutations; serum ... See more keywords
Genotype-phenotype correlation in FMF patients: A "non classic" recessive autosomal or "atypical" dominant autosomal inheritance?
Sign Up to like & getrecommendations! Published in 2018 at "Gene"
DOI: 10.1016/j.gene.2017.10.068
Abstract: BACKGROUND Uncertainty remains on the pathogenetic mechanisms, model of inheritance as well as genotype-phenotype correlation of FMF disease. OBJECTIVE To investigate the impact of genetic factors on the FMF phenotype and the disease inheritance model.… read more here.
Keywords: phenotype; inheritance; genotype; met680ile ... See more keywords
The PRY/SPRY domain of pyrin/TRIM20 interacts with β2-microglobulin to promote inflammasome formation
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-03073-6
Abstract: Pyrin/TRIM20 is expressed in the neutrophils and monocytes/macrophages and regulates caspase-1 activation and interleukin-1β maturation. Although the mutations in the PRY/SPRY domain of pyrin cause familial Mediterranean fever (FMF), the mechanism of how mutated pyrin… read more here.
Keywords: fmf; pry spry; domain; pyrin trim20 ... See more keywords
Fibrinogen-to-Albumin Ratio in Familial Mediterranean Fever: Association with Subclinical Inflammation.
Sign Up to like & getrecommendations! Published in 2021 at "Klinische Padiatrie"
DOI: 10.1055/a-1610-9745
Abstract: BACKGROUND Familial Mediterranean fever (FMF) is the most seen monogenic periodic fever syndrome characterised by bouts of fever and serositis. It is known that subclinical inflammation (SI) can persist in the symptom-free period and lead… read more here.
Keywords: die; fibrinogen; fever; der ... See more keywords
Monocyte secretory profiling in a clinical and MEFV genotype-characterized cohort of Danish familial Mediterranean fever patients: diagnostic potential of CCL1 and CXCL1.
Sign Up to like & getrecommendations! Published in 2022 at "Scandinavian Journal of Rheumatology"
DOI: 10.1080/03009742.2022.2028382
Abstract: Objective The autoinflammatory disease familial Mediterranean fever (FMF), characterized by recurrent attacks of sterile fever, serosal, and/or synovial inflammation, is caused by variants in the Mediterranean fever gene, MEFV, coding for the pyrin inflammasome sensor.… read more here.
Keywords: fmf patients; fmf; mefv; mediterranean fever ... See more keywords
Spondyloarthritis associated with familial Mediterranean fever: successful treatment with anakinra.
Sign Up to like & getrecommendations! Published in 2017 at "Rheumatology"
DOI: 10.1093/rheumatology/kew290
Abstract: SIR, FMF is an autosomal recessive, autoinflammatory disorder, with mutations in the MEFV gene. The clinical presentation is characterized by recurrent episodes of fever associated with abdominal, chest, joint and muscular pain [1, 2]. Colchicine… read more here.
Keywords: treatment; anakinra; colchicine; spondyloarthritis ... See more keywords
The Influence of Coexisting Familial Mediterranean Fever on Crohn's Disease: Data From an FMF Endemic Area.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of clinical gastroenterology"
DOI: 10.1097/mcg.0000000000001798
Abstract: GOAL The goal of this study was to evaluate the impact of coexisting familial Mediterranean fever (FMF) on Crohn's disease (CD) patients' phenotype and disease course in an endemic region for FMF. BACKGROUND CD and… read more here.
Keywords: familial mediterranean; disease; fmf; fever ... See more keywords
Elliptical-Core Highly Nonlinear Few-Mode Fiber Based OXC for WDM-MDM Networks
Sign Up to like & getrecommendations! Published in 2021 at "IEEE Journal of Selected Topics in Quantum Electronics"
DOI: 10.1109/jstqe.2020.3012405
Abstract: In order to realize an optical cross-connect (OXC) converting wavelengths and spatial modes into one-dimensional switching ports, we propose an active mode selective conversion without parasitic wavelength conversion, based on the intermodal four-wave mixing (FWM)… read more here.
Keywords: fmf; wdm mdm; core; mdm networks ... See more keywords
Genome sequencing unveils mutational landscape of the familial Mediterranean fever: Potential implications of IL33/ST2 signalling
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.15701
Abstract: Familial Mediterranean fever (FMF) is the most common auto‐inflammatory disease. It is transmitted as autosomal recessive trait with mutations in MEditerranean FeVer (MEFV) gene. Despite a typical clinical expression, many patients have either a single… read more here.
Keywords: mutational landscape; familial mediterranean; genome sequencing; mediterranean fever ... See more keywords
THU0542 Anti-interleukin 1 therapy in FMF amyloidosis: a single center experience (case series)
Sign Up to like & getrecommendations! Published in 2017 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2017-eular.5397
Abstract: Background Recently there is increasing number of reports investigating the efficacy of anti-interleukin-1 (anti-IL1) therapy in AA-amyloidosis. Objectives Here we report our experience in IL-1 blockade in AA amyloidosis secondary to FMF. Methods Twenty nine… read more here.
Keywords: amyloidosis; therapy; thu0542 anti; anti interleukin ... See more keywords