Hydrazine hydrate: A new reagent for Fmoc group removal in solid phase peptide synthesis
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DOI: 10.1016/j.tetlet.2018.11.054
Abstract: Abstract In solid-phase peptide synthesis using the Fmoc/tBu strategy (SPPS-Fmoc/tBu), an orthogonal protection scheme of amino acids is used; specifically, the alpha-amine group is protected by the 9-fluorenylmethyloxycarbonyl (Fmoc) group, which is removed by weak… read more here.
Keywords: fmoc group; hydrazine hydrate; group; group removal ... See more keywords