Fmrp regulates oligodendrocyte lineage cell specification and differentiation
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DOI: 10.1002/glia.24041
Abstract: Neurodevelopment requires the precise integration of a wide variety of neuronal and glial cell types. During early embryonic development, motor neurons and then oligodendrocyte precursor cells (OPCs) are specified from neural progenitors residing in the… read more here.
Keywords: fmrp regulates; cell; specification differentiation; cell specification ... See more keywords
FMRP regulates mRNAs encoding distinct functions in the cell body and dendrites of CA1 pyramidal neurons
Sign Up to like & getrecommendations! Published in 2021 at "eLife"
DOI: 10.7554/elife.71892
Abstract: Neurons rely on translation of synaptic mRNAs in order to generate activity-dependent changes in plasticity. Here, we develop a strategy combining compartment-specific crosslinking immunoprecipitation (CLIP) and translating ribosome affinity purification (TRAP) in conditionally tagged mice… read more here.
Keywords: ca1 pyramidal; fmrp; fmrp targets; fmrp regulates ... See more keywords