TWEAK/Fn14 Activation Participates in Skin Inflammation
Sign Up to like & getrecommendations! Published in 2017 at "Mediators of Inflammation"
DOI: 10.1155/2017/6746870
Abstract: Tumor necrosis factor- (TNF-) like weak inducer of apoptosis (TWEAK) participates in multiple biological activities via binding to its sole receptor—fibroblast growth factor-inducible 14 (Fn14). The TWEAK/Fn14 signaling pathway is activated in skin inflammation and… read more here.
Keywords: fn14 activation; skin inflammation; tweak fn14; tweak ... See more keywords
Lipopolysaccharide Upregulated Intestinal Epithelial Cell Expression of Fn14 and Activation of Fn14 Signaling Amplify Intestinal TLR4-Mediated Inflammation
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2017.00315
Abstract: TLR4 in intestinal epithelial cells has been shown both inflammatory and homeostatic roles following binding of its cognate ligand lipopolysaccharide (LPS). TWEAK-Fn14 axis plays an important role in pathologies caused by excessive or abnormal inflammatory… read more here.
Keywords: intestinal epithelial; fn14; fn14 activation; expression fn14 ... See more keywords