Comprehensive Enantioselectivity Evaluation of Insecticidal Activity and Mammalian Toxicity of Fenobucarb.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.2c00093
Abstract: To comprehensively evaluate the efficiency and risk of the chiral pesticide fenobucarb, the bioactivity, toxicity, and environmental behavior of fenobucarb (FNC) enantiomers were investigated. The results showed that R-FNC possesses 1.8-2.7 times more bioactivity than… read more here.
Keywords: comprehensive enantioselectivity; insecticidal activity; enantioselectivity evaluation; toxicity ... See more keywords
Azvudine is a thymus-homing anti-SARS-CoV-2 drug effective in treating COVID-19 patients
Sign Up to like & getrecommendations! Published in 2021 at "Signal Transduction and Targeted Therapy"
DOI: 10.1038/s41392-021-00835-6
Abstract: Azvudine (FNC) is a nucleoside analog that inhibits HIV-1 RNA-dependent RNA polymerase (RdRp). Recently, we discovered FNC an agent against SARS-CoV-2, and have taken it into Phase III trial for COVID-19 patients. FNC monophosphate analog… read more here.
Keywords: thymus homing; sars cov; fnc; covid patients ... See more keywords
FNC: An Advanced Anticancer Therapeutic or Just an Underdog?
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.820647
Abstract: Azvudine (FNC) is a novel cytidine analogue that has both antiviral and anticancer activities. This minireview focuses on its underlying molecular mechanisms of suppressing viral life cycle and cancer cell growth and discusses applications of… read more here.
Keywords: oncology; anticancer therapeutic; advanced anticancer; fnc ... See more keywords