Articles with "fndc1" as a keyword



Up-regulated FNDC1 accelerates stemness and chemoradiation resistance in colorectal cancer cells.

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Published in 2022 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2022.02.038

Abstract: Neoadjuvant chemoradiation (nCRT) followed by radical surgery is the preferred option for locally advanced colorectal cancer (CRC) treatment. However, chemo/radio-resistance remains a main obstacle in CRC therapy. In the study, we analyzed the mRNA expression… read more here.

Keywords: fndc1; chemoradiation resistance; chemoradiation; crc ... See more keywords

Abstract 4366549: FNDC1 is Implicated in Small and Large-vessel Arterial Disease and Induces Vascular Calcification via PI3K/AKT Signaling and the NAD Salvage Pathway

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Published in 2025 at "Circulation"

DOI: 10.1161/circ.152.suppl_3.4366549

Abstract: Introduction: Vascular calcification is a major contributor to cardiovascular morbidity and mortality, yet the molecular mechanisms of calcification remain poorly defined. Research Question: Here, we aimed to identify novel differentially expressed genes (DEGs) and altered… read more here.

Keywords: disease; small large; vascular calcification; fndc1 ... See more keywords