Palladium Hydride Nanopocket Cubes and Their H2‐Therapy Function in Amplifying Inhibition of Foam Cells to Attenuate Atherosclerosis
Sign Up to like & getrecommendations! Published in 2021 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202104892
Abstract: Foam cells formed by the imbalance between lipid uptake and efflux play a dominant role at all stages of atherosclerotic development. Lipid‐regulation by active agents can reduce atherosclerotic lesions, however only limited therapeutic efficacy has… read more here.
Keywords: palladium hydride; foam cells; nanopocket cubes; nanopocket ... See more keywords
miR‐34a Targets HDAC1‐Regulated H3K9 Acetylation on Lipid Accumulation Induced by Homocysteine in Foam Cells
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26126
Abstract: Hyperhomocysteinemia (HHcy) promotes atherogenesis by modification of histone acetylation patterns and regulation of miRNA expression while the underlying molecular mechanisms are not well known. In this study, we investigated the effects of homocysteine (Hcy) on… read more here.
Keywords: accumulation; acetylation; mir 34a; expression ... See more keywords
Effect of autophagy on ferroptosis in foam cells via Nrf2.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular and cellular biochemistry"
DOI: 10.1007/s11010-021-04347-3
Abstract: The progression of atherosclerotic plaque is accelerated by death of foam cells during the development of the plaque. There are several forms of foam cell death, such as autophagy and ferroptosis forms of cell death… read more here.
Keywords: foam; ferroptosis; foam cells; death ... See more keywords
Mycobacterium marinum infection drives foam cell differentiation in zebrafish infection models
Sign Up to like & getrecommendations! Published in 2018 at "Developmental and Comparative Immunology"
DOI: 10.1016/j.dci.2018.07.022
Abstract: ABSTRACT Host lipid metabolism is an important target for subversion by pathogenic mycobacteria such as Mycobacterium tuberculosis. The appearance of foam cells within the granuloma are well‐characterised effects of chronic tuberculosis. The zebrafish‐Mycobacterium marinum infection… read more here.
Keywords: foam cells; marinum infection; infection; mycobacterium marinum ... See more keywords
GW29-e0857 CML Induces Vascular Smooth Muscle Cell Derived-Foam Cells Formation
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American College of Cardiology"
DOI: 10.1016/j.jacc.2018.08.106
Abstract: To study the effect and mechanism of Ne-carboxymethyllysine (CML) on vascular smooth muscle cells foam cells formation. Primary vascular smooth muscle cells were extracted from the aorta of C57 mice using tissue patching and identified;… read more here.
Keywords: cml; vascular smooth; smooth muscle; cells formation ... See more keywords
CTRP9 alleviates foam cells apoptosis by enhancing cholesterol efflux
Sign Up to like & getrecommendations! Published in 2021 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2020.111138
Abstract: The apoptosis of foam cells leads to instability of atherosclerotic plaques. This study was designed to explore the protective role of CTRP9 in foam cell apoptosis. In our experiment, CTRP9 alleviated foam cell apoptosis. Meanwhile,… read more here.
Keywords: foam cells; ctrp9; cholesterol efflux; apoptosis ... See more keywords
Foam cells promote atherosclerosis progression by releasing CXCL12
Sign Up to like & getrecommendations! Published in 2020 at "Bioscience Reports"
DOI: 10.1042/bsr20193267
Abstract: Abstract Background: Atherosclerosis (AS) is a chronic inflammatory disease that contributes to multiple cardiovascular diseases (CVDs), and foam cell formation plays important roles in the progression of AS. There is an urgent need to identify… read more here.
Keywords: expression; foam; progression; model ... See more keywords
Gastrodin induces lysosomal biogenesis and autophagy to prevent the formation of foam cells via AMPK‐FoxO1‐TFEB signalling axis
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.16600
Abstract: Abnormal accumulation of lipids and massive deposition of foam cells is a primary event in the pathogenesis of atherosclerosis. Recent studies have demonstrated that autophagy and lysosomal function of atherosclerotic macrophages are impaired, which exacerbates… read more here.
Keywords: biogenesis autophagy; foam; foam cells; formation foam ... See more keywords
Leonurine Prevents Atherosclerosis Via Promoting the Expression of ABCA1 and ABCG1 in a Pparγ/Lxrα Signaling Pathway-Dependent Manner
Sign Up to like & getrecommendations! Published in 2017 at "Cellular Physiology and Biochemistry"
DOI: 10.1159/000484031
Abstract: Background/Aims: Previous studies have demonstrated that leonurine, a unique alkaloid compound of Herba leonuri, can exert anti-oxidative and anti-inflammatory effects on the development of atherosclerosis (AS). This study was designed to investigate the effects of… read more here.
Keywords: ppar; cholesterol; ppar lxr; foam cells ... See more keywords
Smooth Muscle Cells Contribute the Majority of Foam Cells in ApoE (Apolipoprotein E)-Deficient Mouse Atherosclerosis
Sign Up to like & getrecommendations! Published in 2019 at "Arteriosclerosis, Thrombosis, and Vascular Biology"
DOI: 10.1161/atvbaha.119.312434
Abstract: Objective— Smooth muscle cells (SMCs) are the most abundant cells in human atherosclerotic lesions and are suggested to contribute at least 50% of atheroma foam cells. In mice, SMCs contribute fewer total lesional cells. The… read more here.
Keywords: foam; biology; smooth muscle; foam cells ... See more keywords
Monitoring deformation mechanism of foam cells in polyethylene foams via optical microscopy: Effect of density and microstructure
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Plastics"
DOI: 10.1177/0021955x18795035
Abstract: The effect of cellular microstructure and density of low-density polyethylene (LDPE) foam during the compressive deformation were evaluated. Progressive foam cell structure deformation at crosshead speed of 10 mm/min was closely monitored and captured using a… read more here.
Keywords: microscopy; foam; density; foam cells ... See more keywords