Prototype foamy virus integrase is promiscuous for target choice
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.07.031
Abstract: Retroviruses have two essential activities: reverse transcription and integration. The viral protein integrase (IN) covalently joins the viral cDNA genome to the host DNA. Prototype foamy virus (PFV) IN has become a model of retroviral… read more here.
Keywords: prototype foamy; virus integrase; foamy virus; target ... See more keywords
Identification of Cartilaginous Fish Endogenous Foamy Virus Rooting to Vertebrate Counterparts
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Virology"
DOI: 10.1128/jvi.01816-22
Abstract: Although foamy viruses (FVs) have been found in major branches of vertebrates, the presence of these viruses in cartilaginous fish, the most basal living vertebrates with jaws, remains to be explored. This study revealed a… read more here.
Keywords: cartilaginous fish; fvs; fish endogenous; foamy virus ... See more keywords
SGK1, a Serine/Threonine Kinase, Inhibits Prototype Foamy Virus Replication
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.01995-21
Abstract: Foamy viruses can integrate into the host chromosome and are nonpathogenic in natural hosts or in experimentally infected animals. Therefore, foamy viruses are considered to be safe and efficient gene transfer vectors. ABSTRACT Foamy viruses… read more here.
Keywords: replication; foamy virus; foamy viruses; host ... See more keywords
Foamy virus zoonotic infections
Sign Up to like & getrecommendations! Published in 2017 at "Retrovirology"
DOI: 10.1186/s12977-017-0379-9
Abstract: BackgroundFoamy viruses (FV) are ancient complex retroviruses that differ from orthoretroviruses such as human immunodeficiency virus (HIV) and murine leukemia virus (MLV) and comprise a distinct subfamily of retroviruses, the Spumaretrovirinae. FV are ubiquitous in… read more here.
Keywords: zoonotic infections; virus; foamy virus; virus zoonotic ... See more keywords
Feline Foamy Virus is Highly Prevalent in Free-Ranging Puma concolor from Colorado, Florida and Southern California
Sign Up to like & getrecommendations! Published in 2019 at "Viruses"
DOI: 10.3390/v11040359
Abstract: Feline foamy virus (FFV) is a retrovirus that has been detected in multiple feline species, including domestic cats (Felis catus) and pumas (Puma concolor). FFV results in persistent infection but is generally thought to be… read more here.
Keywords: southern california; colorado; feline foamy; puma ... See more keywords
Occurrence of Equine Foamy Virus Infection in Horses from Poland
Sign Up to like & getrecommendations! Published in 2022 at "Viruses"
DOI: 10.3390/v14091973
Abstract: Equine foamy virus (EFVeca) is a foamy virus of non-primate origin and among the least-studied members of this retroviral subfamily. By sequence comparison, EFVeca shows the highest similarity to bovine foamy virus. In contrast to… read more here.
Keywords: efveca infections; efveca; horses poland; equine foamy ... See more keywords
Foamy Virus Integrase in Development of Viral Vector for Gene Therapy.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of microbiology and biotechnology"
DOI: 10.4014/jmb.2003.03046
Abstract: Due to the broad host suitability of viral vectors and their high gene delivery capacity, many researchers are focusing on viral vector-mediated gene therapy. Among the retroviruses, foamy viruses have been considered potential gene therapy… read more here.
Keywords: integrase; vector; gene therapy; foamy virus ... See more keywords