SGK1, a Serine/Threonine Kinase, Inhibits Prototype Foamy Virus Replication
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DOI: 10.1128/spectrum.01995-21
Abstract: Foamy viruses can integrate into the host chromosome and are nonpathogenic in natural hosts or in experimentally infected animals. Therefore, foamy viruses are considered to be safe and efficient gene transfer vectors. ABSTRACT Foamy viruses… read more here.
Keywords: replication; foamy virus; foamy viruses; host ... See more keywords
Potent neutralizing antibodies in humans infected with zoonotic simian foamy viruses target conserved epitopes located in the dimorphic domain of the surface envelope protein
Sign Up to like & getrecommendations! Published in 2018 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1007293
Abstract: Human diseases of zoonotic origin are a major public health problem. Simian foamy viruses (SFVs) are complex retroviruses which are currently spilling over to humans. Replication-competent SFVs persist over the lifetime of their human hosts,… read more here.
Keywords: simian foamy; sfv; neutralizing antibodies; foamy viruses ... See more keywords
Structural Insights on Retroviral DNA Integration: Learning from Foamy Viruses
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DOI: 10.3390/v11090770
Abstract: Foamy viruses (FV) are retroviruses belonging to the Spumaretrovirinae subfamily. They are non-pathogenic viruses endemic in several mammalian hosts like non-human primates, felines, bovines, and equines. Retroviral DNA integration is a mandatory step and constitutes… read more here.
Keywords: dna integration; retroviral dna; insights retroviral; integration ... See more keywords
Foamy Viruses, Bet, and APOBEC3 Restriction
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DOI: 10.3390/v13030504
Abstract: Non-human primates (NHP) are an important source of viruses that can spillover to humans and, after adaptation, spread through the host population. Whereas HIV-1 and HTLV-1 emerged as retroviral pathogens in humans, a unique class… read more here.
Keywords: restriction; viruses bet; apobec3 restriction; biology ... See more keywords