Association of Dementia Risk With Focal Epilepsy and Modifiable Cardiovascular Risk Factors
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Neurology"
DOI: 10.1001/jamaneurol.2023.0339
Abstract: This cross-sectional study examines data from the UK Biobank to explore the association between focal epilepsy compared with stroke or migraine and the risk of developing dementia and how that risk is affected by modifiable… read more here.
Keywords: modifiable cardiovascular; risk factors; risk; cardiovascular risk ... See more keywords
The localization and lateralization of fear aura and its surgical prognostic value in patients with focal epilepsy
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51607
Abstract: Fear aura has traditionally been considered relevant to epileptic discharges from mesial temporal areas, and few studies have investigated its effect on surgical outcome in drug‐resistant epilepsy. We aim to assess the localizing and lateralizing… read more here.
Keywords: localization lateralization; fear aura; fear; value ... See more keywords
SEEG‐RFTC in patients with refractory focal epilepsy: real‐world outcomes from 121 cases
Sign Up to like & getrecommendations! Published in 2024 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.52117
Abstract: Radiofrequency thermocoagulation (RFTC) has emerged as an effective and safe treatment method for patients with refractory focal epilepsy, when stereo‐electroencephalography (SEEG) is implanted. Although real‐world research results are still limited, a considerable number of patients… read more here.
Keywords: seeg rftc; patients refractory; real world; focal epilepsy ... See more keywords
Nuclei‐Specific Amygdala Enlargement Is Linked to Psychiatric Comorbidities in Drug‐Resistant Focal Epilepsy
Sign Up to like & getrecommendations! Published in 2025 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.70071
Abstract: Amygdala enlargement has been the subject of controversial studies regarding its significance in terms of pathogenicity both in epilepsy and in psychiatric comorbidities such as anxiety, depression, and post‐traumatic stress disorder. However, no causal link… read more here.
Keywords: focal epilepsy; resistant focal; drug resistant; psychiatric comorbidities ... See more keywords
Can we predict drug response by volumes of the corpus callosum in newly diagnosed focal epilepsy?
Sign Up to like & getrecommendations! Published in 2017 at "Brain and Behavior"
DOI: 10.1002/brb3.751
Abstract: The aim of this study was to investigate whether volumes of the corpus callosum could predict a response to antiepileptic drugs in patients with newly diagnosed focal epilepsy. read more here.
Keywords: newly diagnosed; response; corpus callosum; focal epilepsy ... See more keywords
Real‐world anti‐seizure treatment and adverse events among individuals living with drug‐resistant focal epilepsy in the United States
Sign Up to like & getrecommendations! Published in 2024 at "Epilepsia Open"
DOI: 10.1002/epi4.12967
Abstract: This study aimed to understand how people living with drug‐resistant focal epilepsy (DRE) navigate through lines of antiseizure medications (ASM) and experience adverse events (AEs) in the real‐world setting in the United States. read more here.
Keywords: adverse events; real world; focal epilepsy; resistant focal ... See more keywords
Efficacy and safety of add‐on antiseizure medications for focal epilepsy: A network meta‐analysis
Sign Up to like & getrecommendations! Published in 2024 at "Epilepsia Open"
DOI: 10.1002/epi4.12997
Abstract: Several antiseizure medications (ASMs) have been approved for the treatment of focal epilepsy. However, there is a paucity of evidence on direct comparison of ASMs. We evaluated the comparative efficacy and safety of all approved… read more here.
Keywords: antiseizure medications; meta analysis; epilepsy; focal epilepsy ... See more keywords
Systematic literature review of the humanistic and economic burden of focal epilepsy and primary generalized tonic–clonic seizures in adults
Sign Up to like & getrecommendations! Published in 2024 at "Epilepsia Open"
DOI: 10.1002/epi4.13011
Abstract: This systematic literature review (SLR) assessed the humanistic and economic burden of focal epilepsy and primary generalized tonic–clonic seizures (PGTCS) in adults to evaluate these domains in both populations and identify evidence gaps to inform… read more here.
Keywords: epilepsy; economic burden; focal epilepsy; burden ... See more keywords
Radiofrequency thermocoagulation in focal epilepsy: A retrospective cohort study
Sign Up to like & getrecommendations! Published in 2025 at "Epilepsia Open"
DOI: 10.1002/epi4.70009
Abstract: Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐guided RFTC) has been increasingly used as diagnostic and therapeutic approach for drug‐resistant focal epilepsies (DREs). We aimed to describe seizure outcomes of RFTC before and after further neurosurgical intervention. read more here.
Keywords: radiofrequency thermocoagulation; focal epilepsy; thermocoagulation focal; radiofrequency ... See more keywords
The predictive value of hypometabolism in focal epilepsy: a prospective study in surgical candidates
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-019-04356-x
Abstract: PurposeFDG PET is an established tool in presurgical epilepsy evaluation, but it is most often used selectively in patients with discordant MRI and EEG results. Interpretation is complicated by the presence of remote or multiple… read more here.
Keywords: epilepsy; outcome; hypometabolism; focal epilepsy ... See more keywords
Lacosamide treatment of childhood refractory focal epilepsy: the first reported side effect in paediatric patients
Sign Up to like & getrecommendations! Published in 2017 at "Child's Nervous System"
DOI: 10.1007/s00381-017-3586-8
Abstract: PurposeLacosamide (LCM) is an effective antiepileptic drug (AED) approved for the treatment of focal epilepsy in both children and adults. The aim of this observational study was to review our centre’s experience with LCM and… read more here.
Keywords: treatment; focal epilepsy; refractory focal; paediatric patients ... See more keywords