Integration of genomic analysis and transcript expression of ABCC8 and KCNJ11 in focal form of congenital hyperinsulinism
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DOI: 10.3389/fendo.2022.1015244
Abstract: Background The focal form of CHI is caused by an autosomal recessive pathogenic variant affecting the paternal homologue of genes ABCC8 or KCNJ11 and a second somatic event specifically occurring in the affected islet of… read more here.
Keywords: focal form; focal lesions; expression; analysis ... See more keywords
Laparoscopic Surgery for Focal-Form Congenital Hyperinsulinism Located in Pancreatic Head
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DOI: 10.3389/fped.2022.919238
Abstract: Background and Aims Congenital hyperinsulinism of infancy (CHI) is a rare condition that may cause irreversible severe neurological damage in infants. For children in whom medical management fails, partial or near-total pancreatectomy is then required… read more here.
Keywords: congenital hyperinsulinism; head resection; head; focal form ... See more keywords