Comparing Kidney Health Outcomes in Children, Adolescents, and Adults With Focal Segmental Glomerulosclerosis
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.28701
Abstract: Key Points Question Are kidney health outcomes different in children and adolescents compared with adults with focal segmental glomerulosclerosis (FSGS)? Findings This cohort study with 482 patients from 3 independent cohorts found no significant differences… read more here.
Keywords: kidney health; focal segmental; kidney; health outcomes ... See more keywords
Removal of focal segmental glomerulosclerosis (FSGS) factor suPAR using CytoSorb
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Apheresis"
DOI: 10.1002/jca.21538
Abstract: Treatment of primary focal segmental glomerulosclerosis (FSGS) and its recurrence after kidney transplantation associated with rapid deterioration of kidney function remains to be challenging despite advances in immunosuppressive therapy. The presence of circulating factors has… read more here.
Keywords: focal segmental; glomerulosclerosis fsgs; using cytosorb; supar ... See more keywords
Mutations in INF2 may be associated with renal histology other than focal segmental glomerulosclerosis
Sign Up to like & getrecommendations! Published in 2017 at "Pediatric Nephrology"
DOI: 10.1007/s00467-017-3811-4
Abstract: BackgroundIn 2010, INF2 mutations were associated with autosomal-dominant focal segmental glomerulosclerosis (FSGS), clinically presenting with moderate proteinuria in adolescence. However, in the meantime, cases with more severe clinical courses have been described, including progression to… read more here.
Keywords: focal segmental; segmental glomerulosclerosis; mutations inf2; renal histology ... See more keywords
Association of a de novo nonsense mutation of the TRIM8 gene with childhood-onset focal segmental glomerulosclerosis
Sign Up to like & getrecommendations! Published in 2020 at "Pediatric Nephrology"
DOI: 10.1007/s00467-020-04525-3
Abstract: Background Focal segmental glomerulosclerosis (FSGS) is an etiologically heterogeneous disorder. Genetic FSGS may be either limited to the kidney or part of a genetic syndrome with other systemic involvement. At least 21 and 34 genes… read more here.
Keywords: focal segmental; trim8 gene; gene; childhood onset ... See more keywords
Recent advances of animal model of focal segmental glomerulosclerosis
Sign Up to like & getrecommendations! Published in 2018 at "Clinical and Experimental Nephrology"
DOI: 10.1007/s10157-018-1552-8
Abstract: In the last decade, great advances have been made in understanding the genetic basis for focal segmental glomerulosclerosis (FSGS). Animal models using specific gene disruption of the slit diaphragm and cytoskeleton of the foot process… read more here.
Keywords: focal segmental; segmental glomerulosclerosis; animal; fsgs ... See more keywords
miR-150 inhibitor ameliorates adriamycin-induced focal segmental glomerulosclerosis.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.11.096
Abstract: Focal segmental glomerulosclerosis (FSGS) is the most common cause of adult nephrotic syndrome in USA. Its mechanisms remain unclear and the effective treatment lacks. We previously reported that upregulation of microRNA (miR)-150 in human podocytes… read more here.
Keywords: focal segmental; anti mir; mir; adriamycin induced ... See more keywords
CircZNF609 is involved in the pathogenesis of focal segmental glomerulosclerosis by sponging miR-615-5p.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.07.066
Abstract: As a set of distinct syndromes, focal segmental glomerulosclerosis (FSGS) is the most common cause of adult nephrotic syndrome with diverse mechanisms. We recently found that expression of the circular RNA circZNF609 is increased in… read more here.
Keywords: focal segmental; sponging mir; segmental glomerulosclerosis; circznf609 ... See more keywords
Renal ultrasound findings secondary to COVID-19 related collapsing focal segmental glomerulosclerosis – A case report
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Imaging"
DOI: 10.1016/j.clinimag.2020.11.011
Abstract: SARS-CoV-2 (COVID-19) is well known to have extrapulmonary manifestations, including acute renal failure. While radiologic findings of COVID-19 pulmonary-involvement have been described, renal findings associated with COVID-19 have not. We present a case of a… read more here.
Keywords: focal segmental; secondary covid; case; segmental glomerulosclerosis ... See more keywords
Selective bilateral renal artery embolization with tris-acryl microspheres in focal segmental glomerulosclerosis.
Sign Up to like & getrecommendations! Published in 2017 at "Diagnostic and interventional imaging"
DOI: 10.1016/j.diii.2016.06.022
Abstract: Renal artery embolization (RAE) was originally used only in patients with symptomatic hematuria and palliation of metastatic renal cancer. Nowadays, RAE is used for the treatment of renal medical diseases, renal lesions such as angiomyolipoma… read more here.
Keywords: focal segmental; artery embolization; renal artery; segmental glomerulosclerosis ... See more keywords
Study Design of the Phase 3 Sparsentan Versus Irbesartan (DUPLEX) Study in Patients With Focal Segmental Glomerulosclerosis
Sign Up to like & getrecommendations! Published in 2020 at "Kidney International Reports"
DOI: 10.1016/j.ekir.2019.12.017
Abstract: Introduction Focal segmental glomerulosclerosis (FSGS), a histologic lesion in the kidney caused by varied pathophysiological processes, leads to end-stage kidney disease in a large proportion of patients. Sparsentan is a first-in-class orally active compound combining… read more here.
Keywords: focal segmental; phase; study; receptor ... See more keywords
CD44 is required for the pathogenesis of experimental crescentic glomerulonephritis and collapsing focal segmental glomerulosclerosis.
Sign Up to like & getrecommendations! Published in 2018 at "Kidney international"
DOI: 10.1016/j.kint.2017.09.020
Abstract: A key feature of glomerular diseases such as crescentic glomerulonephritis and focal segmental glomerulosclerosis is the activation, migration and proliferation of parietal epithelial cells. CD44-positive activated parietal epithelial cells have been identified in proliferative cellular… read more here.
Keywords: focal segmental; crescentic glomerulonephritis; parietal epithelial; segmental glomerulosclerosis ... See more keywords