Novel aspects of the assembly and activation of inflammasomes with focus on the NLRC4 inflammasome
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DOI: 10.1093/intimm/dxy009
Abstract: Inflammasomes are multiprotein structures that activate caspase-1, support secretion of pro-inflammatory cytokines, IL-1β and IL-18, and also induce inflammatory programmed cell death, termed pyoptosis. Inflammasomes are activated in response to the detection of endogenous and… read more here.
Keywords: novel aspects; aspects assembly; inflammasomes focus; focus nlrc4 ... See more keywords