Articles with "focused design" as a keyword



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Focused Design of Novel Cyclic Peptides Endowed with GABARAP-Inhibiting Activity

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms23095070

Abstract: (1) Background: Disfunctions in autophagy machinery have been identified in various conditions, including neurodegenerative diseases, cancer, and inflammation. Among mammalian autophagy proteins, the Atg8 family member GABARAP has been shown to be greatly involved in… read more here.

Keywords: cyclic peptides; gabarap; design; activity ... See more keywords