A Focused DNA-Encoded Chemical Library for the Discovery of Inhibitors of NAD+-Dependent Enzymes.
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DOI: 10.1021/jacs.8b08039
Abstract: DNA-encoded chemical libraries are increasingly used in pharmaceutical research because they enable the rapid discovery of synthetic protein ligands. Here we explored whether target-class focused DNA-encoded chemical libraries can be cost-effective tools to achieve robust… read more here.
Keywords: chemical library; dna; dna encoded; focused dna ... See more keywords