TLRs induce Th1/Th2 responses by affecting the secretion of CCL2 at the maternal-foetal interface.
Sign Up to like & getrecommendations! Published in 2021 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2021.108070
Abstract: RESEARCH QUESTION In previous studies, we demonstrated that the human decidua and decidual stromal cells express high levels of CCL2 (chemokine (C-C motif) ligand 2, also known as monocyte chemotactic protein-1) and its receptor CCR2… read more here.
Keywords: secretion; maternal foetal; th1 th2; foetal interface ... See more keywords
The role of maternal-foetal interface inflammation mediated by NLRP3 inflammasome in the pathogenesis of recurrent spontaneous abortion.
Sign Up to like & getrecommendations! Published in 2020 at "Placenta"
DOI: 10.1016/j.placenta.2020.09.067
Abstract: INTRODUCTION Approximately half of the recurrent spontaneous abortions (RSAs) that remain unidentified to date may be closely related to inflammation. Our previous study found excessive NLRP3 inflammasomes in RSA patients. Here, we investigated further the… read more here.
Keywords: recurrent spontaneous; maternal foetal; inflammation; foetal interface ... See more keywords