The Folate Cycle Enzyme MTHFR is a Critical Regulator of Cell Response to MYC-Targeting Therapies.
Sign Up to like & getrecommendations! Published in 2020 at "Cancer discovery"
DOI: 10.1158/2159-8290.cd-19-0970
Abstract: Deciphering the impact of metabolic intervention on response to anticancer therapy may elucidate a path toward improved clinical responses. Here, we identify amino acid-related pathways connected to the folate cycle whose activation predicts sensitivity to… read more here.
Keywords: cycle; folate cycle; cycle enzyme; targeting therapies ... See more keywords
Associations of variants of folate cycle genes with features of the clinical course of severe intraventricular hemorrhages in premature infants.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of neonatal-perinatal medicine"
DOI: 10.3233/npm-210962
Abstract: BACKGROUND Summary data indicate that it has increased attention to the study of the role of the folate cycle and the genes encoding its key components in the complicated course of the neonatal period in… read more here.
Keywords: cycle genes; course; premature infants; folate cycle ... See more keywords