Alginate based tamoxifen/metal dual core-folate decorated shell: Nanocomposite targeted therapy for breast cancer via ROS-driven NF-κB pathway modulation.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2019.12.266
Abstract: Breast cancer endocrine resistance prevents unleashing full capabilities of Tamoxifen (TMX), besides TMX off-target side effects on healthy tissue. In this study, we engineered TMX nanocomposite via co-loading it on alginate-based silver nanoparticles and embedding… read more here.
Keywords: cancer; alginate based; folate decorated; breast cancer ... See more keywords
Folate decorated polymeric micelles for targeted delivery of the kinase inhibitor dactolisib to cancer cells.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2020.119305
Abstract: One of the main challenges in clinical translation of polymeric micelles is retention of the drug in the nanocarrier system upon its systemic administration. Core crosslinking and coupling of the drug to the micellar backbone… read more here.
Keywords: folate decorated; kinase; chemistry; inhibitor dactolisib ... See more keywords
Synthesis and characterization of folate decorated albumin bio-conjugate nanoparticles loaded with a synthetic curcumin difluorinated analogue.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of colloid and interface science"
DOI: 10.1016/j.jcis.2017.01.092
Abstract: Albumin-bound paclitaxel colloidal nanoparticle (Abraxane®) is an FDA approved anticancer formulation available in the market. It is a suspension which is currently used therapeutically for treating cancers of the breast, lung, and pancreas among others.… read more here.
Keywords: synthetic curcumin; curcumin difluorinated; folate decorated; decorated albumin ... See more keywords
Folate-decorated and NIR-activated nanoparticles based on platinum(IV) prodrugs for targeted therapy of ovarian cancer
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Microencapsulation"
DOI: 10.1080/02652048.2017.1393114
Abstract: Abstract Platinum-based drugs are used to treat a variety of cancers but have many side effects such as nephrotoxicity and neurotoxicity. A folate-decorated nanoparticles system with a good drug payload can selectively deliver drugs into… read more here.
Keywords: platinum; cancer; activated nanoparticles; folate decorated ... See more keywords