Folate transporter expression in placenta from pregnancies complicated with birth defects.
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DOI: 10.1002/bdr2.1356
Abstract: BACKGROUND Folate plays a fundamental role for fetal development, participating in cell division, embryogenesis, and fetal growth. The fetus depends on maternal supply of folate across the placenta. The objective of this study was to… read more here.
Keywords: folate transporter; birth defects; pregnancies complicated; expression ... See more keywords
High-fat diet consumption reduces hepatic folate transporter expression via nuclear respiratory factor-1
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Molecular Medicine"
DOI: 10.1007/s00109-018-1688-8
Abstract: Folate is an essential micronutrient for biological function. The liver, a primary organ for folate metabolism and storage, plays an important role in folate homeostasis. Proton-coupled folate transporter (PCFT) and reduced folate carrier (RFC) are… read more here.
Keywords: folate; fat; high fat; expression ... See more keywords
Widening the phenotypic spectrum – Non epileptic presentation of folate transporter deficiency
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Neuroscience"
DOI: 10.1016/j.jocn.2018.10.075
Abstract: INTRODUCTION Folate is essential for production of DNA, neurotransmitters and myelin and regulation of genetic activity. A specific transporter protein is required to transport folate from blood to CSF. Various inherited brain-specific folate transport defects… read more here.
Keywords: transporter deficiency; folate; non epileptic; folate transporter ... See more keywords
Impact of hypoxia on chemoresistance of mesothelioma mediated by the proton-coupled folate transporter, and preclinical activity of new anti-LDH-A compounds
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DOI: 10.1038/s41416-020-0912-9
Abstract: Background Expression of proton-coupled folate transporter (PCFT) is associated with survival of mesothelioma patients treated with pemetrexed, and is reduced by hypoxia, prompting studies to elucidate their correlation. Methods Modulation of glycolytic gene expression was… read more here.
Keywords: mesothelioma; coupled folate; proton coupled; ldh ... See more keywords