Insects evolved a monomeric histone-fold domain in the CENP-T protein family
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DOI: 10.1038/s44319-025-00603-5
Abstract: The histone fold domain (HFD) is a conserved protein interaction module that requires stabilization through a handshake interaction with an HFD partner. All HFD proteins known to date form obligate dimers to shield the extensive… read more here.
Keywords: cenp; hfd; fold domain; histone fold ... See more keywords
Slower diffusion and anomalous association of R453W lamin A protein alter nuclear architecture in AD-EDMD
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DOI: 10.1039/d2ra05620h
Abstract: Lamins maintain the shape and rigidity of the nucleus in the form of a proteinaceous scaffold underneath the inner nuclear membrane (INM) and provide anchorage to chromatin and other nuclear proteins. Mutations in the human… read more here.
Keywords: association r453w; fold domain; anomalous association; diffusion anomalous ... See more keywords