Patterns of Antifungal Resistance in Adult Patients With Fungal Keratitis in South India: A Post Hoc Analysis of 3 Randomized Clinical Trials.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA ophthalmology"
DOI: 10.1001/jamaophthalmol.2021.5765
Abstract: Importance Antifungal resistance has been shown to impact treatment success, but research analyzing antifungal resistance is scarce. Objective To evaluate changes in antifungal resistance over time. Design, Setting, and Participants Ad hoc analysis of 3… read more here.
Keywords: hoc analysis; antifungal resistance; fold increase; resistance ... See more keywords
Nampt activator P7C3 ameliorates diabetes and improves skeletal muscle function modulating cell metabolism and lipid mediators.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of cachexia, sarcopenia and muscle"
DOI: 10.1002/jcsm.12887
Abstract: BACKGROUND Nicotinamide phosphoribosyltransferase (Nampt), a key enzyme in NAD salvage pathway is decreased in metabolic diseases, and its precise role in skeletal muscle function is not known. We tested the hypothesis, Nampt activation by P7C3… read more here.
Keywords: fold increase; muscle; p7c3; p7c3 mice ... See more keywords
Exposure to neonicotinoids and serum testosterone in men, women, and children
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology"
DOI: 10.1002/tox.23503
Abstract: Neonicotinoids are the most used pesticides in the world and, despite being harmful to honeybees, they are considered safe for mammals. However, they have been associated with decreasing testosterone levels in several experimental animal models.… read more here.
Keywords: increase urinary; lower fold; serum testosterone; fold increase ... See more keywords
Nitrogen uptake pattern of herbaceous plants: coping strategies in altered neighbor species
Sign Up to like & getrecommendations! Published in 2017 at "Biology and Fertility of Soils"
DOI: 10.1007/s00374-017-1230-0
Abstract: The mechanisms for maintaining the species diversity of plant communities under conditions of resource limitation is an important subject in ecology. How interspecific relationships influence the pattern of nutrient absorption by coexisting species in N-limited… read more here.
Keywords: fold increase; nitrogen uptake; neighbor species; neighbor ... See more keywords
Using SARS-CoV-2 nucleoprotein antibodies to detect (re)infection
Sign Up to like & getrecommendations! Published in 2025 at "Epidemiology and Infection"
DOI: 10.1017/s095026882500010x
Abstract: Abstract We assessed the validity of serum total anti-nucleoprotein Immunoglobulin (N-antibodies) to identify SARS-CoV-2 (re)infections by estimating the persistence of N-antibody seropositivity and boosting following infection. From a prospective Dutch cohort study (VASCO), we included… read more here.
Keywords: sars cov; infection; first sample; fold increase ... See more keywords
Comparison of Adaptive Neuroprotective Mechanisms of Sulforaphane and its Interconversion Product Erucin in in Vitro and in Vivo Models of Parkinson's Disease.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.7b04641
Abstract: Several studies suggest that an increase of glutathione (GSH) through activation of the transcriptional nuclear factor (erythroid-derived 2)-like 2 (Nrf2) in the dopaminergic neurons may be a promising neuroprotective strategy in Parkinson's disease (PD). Among… read more here.
Keywords: neuroprotective effects; fold increase; comparison adaptive; parkinson disease ... See more keywords
Four-fold increase in solar forcing on snow in western U.S. burned forests since 1999
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-09935-y
Abstract: Forest fires are increasing across the American West due to climate warming and fire suppression. Accelerated snow melt occurs in burned forests due to increased light transmission through the canopy and decreased snow albedo from… read more here.
Keywords: fold increase; burned forests; increase solar; four fold ... See more keywords
Novel pyrazoline and pyrazole “turn on” fluorescent sensors selective for Zn2+/Cd2+ at λem 480 nm and Fe3+/Fe2+ at λem 465 nm in MeCN
Sign Up to like & getrecommendations! Published in 2024 at "RSC Advances"
DOI: 10.1039/d4ra00036f
Abstract: A small series of simple pyrazoline and pyrazole based sensors, all derived from the same chalcone precursors, were synthesised, characterised and screened for their fluorescence “turn on” properties in the presence of multiple metals. Pyrazole… read more here.
Keywords: pyrazoline pyrazole; fold increase; fe3; pyrazole ... See more keywords
THU0050 CXCL13 IS A KEY DRIVER FOR MIGRATION AND DIFFERENTIATION OF REGULATORY B CELLS
Sign Up to like & getrecommendations! Published in 2020 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2020-eular.3544
Abstract: Regulatory B cells in human still need to be characterized. Given the absence of a phenotypical definition of these cells, a functional definition based on their ability to secrete IL-10 is often used (corresponding to… read more here.
Keywords: migration; fold increase; ctl patients; b10 cells ... See more keywords
Investigating the interplay between LIGHT and HIF in inflammatory fibroblast responses
Sign Up to like & getrecommendations! Published in 2024 at "Physiology"
DOI: 10.1152/physiol.2024.39.s1.1116
Abstract: Introduction: Intestinal fibroblast differentiation into an inflammatory phenotype likely plays a key role in Inflammatory Bowel Disease (IBD). However, the mechanisms that control this process are poorly understood. The cytokine TNFSF14 (LIGHT) drives inflammatory fibroblast… read more here.
Keywords: physiology; inflammatory; inflammatory fibroblast; fold increase ... See more keywords
Ex Vivo Expansion with E478 Increases the Rate of CRISPR-Mediated Homology Directed Repair of the Beta-Globin Gene in Human Hematopoietic Stem Cells By >10-Fold and Improves In Vivo Engraftment By >120-Fold
Sign Up to like & getrecommendations! Published in 2019 at "Blood"
DOI: 10.1182/blood-2019-131157
Abstract: Background . Site-specific gene correction of hematopoietic stem cells (HSCs) via homology directed repair (HDR) has the potential to precisely repair defective genes and provide life-long cures for a variety of blood-based diseases. It is… read more here.
Keywords: expansion; hdr; fold increase; e478 ... See more keywords