Articles with "fold switch" as a keyword



Aromatic–aromatic interactions drive fold switch of GA95 and GB95 with three residue difference

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Published in 2024 at "Chemical Science"

DOI: 10.1039/d4sc04951a

Abstract: Proteins typically adopt a single fold to carry out their function, but metamorphic proteins, with multiple folding states, defy this norm. Deciphering the mechanism of conformational interconversion of metamorphic proteins is challenging. Herein, we employed… read more here.

Keywords: drive fold; fold switch; ga95 gb95; interactions drive ... See more keywords