Downhill (Un)Folding Coupled to Binding as Mechanism for Engineering Broadband Protein Conformational Transducers.
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DOI: 10.1021/acssynbio.0c00190
Abstract: Canonical proteins fold and function as conformational switches that toggle between their folded (on) and unfolded (off) states, a mechanism that also provides the basis for engineering transducers for biosensor applications. One of the limitations… read more here.
Keywords: engineering; coupled binding; folding coupled; downhill folding ... See more keywords