Predicting 3D genome folding from DNA sequence with Akita
Sign Up to like & getrecommendations! Published in 2020 at "Nature methods"
DOI: 10.1038/s41592-020-0958-x
Abstract: In interphase, the human genome sequence folds in three dimensions into a rich variety of locus-specific contact patterns. Cohesin and CTCF are key regulators; perturbing the levels of either greatly disrupts genome-wide folding as assayed… read more here.
Keywords: genome folding; predicting genome; folding dna; dna sequence ... See more keywords
The sequence of events during folding of a DNA origami
Sign Up to like & getrecommendations! Published in 2019 at "Science Advances"
DOI: 10.1126/sciadv.aaw1412
Abstract: The folding pathway of a DNA origami unveiled in real time, strand by strand, and terminus by terminus. We provide a comprehensive reference dataset of the kinetics of a multilayer DNA origami folding. To this… read more here.
Keywords: origami object; dna; folding dna; dna origami ... See more keywords
Oral Collagen Drink for Antiaging: Antioxidation, Facilitation of the Increase of Collagen Synthesis, and Improvement of Protein Folding and DNA Repair in Human Skin Fibroblasts
Sign Up to like & getrecommendations! Published in 2020 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2020/8031795
Abstract: This work unveils a fish collagen drink for improvement of skin aging. Previous studies frequently discussed the skin aging from the angle of the representative characteristics of collagen loss and the oxidative-induced expression of proteolytic… read more here.
Keywords: collagen; folding dna; protein folding; collagen drink ... See more keywords